Human Anti-HAVCR1 Recombinant Antibody; Fab Fragment (HPAB-1722-FY-F(E)) (CAT#: HPAB-1722-FY-F(E))
Provided is a recombinant human antibody Fab fragment that recognizes HAVCR1. The antibody was purified by affinity chromatography. The full length IgG has an affinity of about 0.8 nM.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7173/if_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7173/if_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_3.jpg
Figure 3 Rectum
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_4_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_4_3.jpg
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_9_4.jpg
Figure 5 Kidney
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_5.jpg
(Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_7_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75697/159393_A_5_6.jpg
Figure 7 RNA cell line category: Group enriched (A549, CACO-2, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113249-HAVCR1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113249-HAVCR1
Specifications
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human HAVCR1
- Species Reactivity
- Human
- Applications
- FC, ELISA
- Related Disease
- Autoimmune disease
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Hepatitis A Virus Cellular Receptor 1; Kidney Injury Molecule 1; T-Cell Immunoglobulin Mucin Family Member 1; T-Cell Immunoglobulin Mucin Receptor 1; T-Cell Membrane Protein 1; HAVCR-1; TIMD-1; KIM-1; TIM-1
- Gene ID
- 26762
- UniProt ID
- Q96D42
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Agonistic Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3508z | Mouse Anti-HAVCR1 Recombinant Antibody (clone 40H12) | WB, ELISA, FC | Mouse IgG1 |
| HPAB-0192CQ | Human Anti-HAVCR1 Recombinant Antibody (HPAB-0192CQ) | ELISA, IHC, FC | Human IgG4, κ |
| HPAB-0193CQ | Human Anti-HAVCR1 Recombinant Antibody (HPAB-0193CQ) | ELISA, IHC, FC, FuncS | Human IgG4, κ |
| HPAB-0194CQ | Human Anti-HAVCR1 Recombinant Antibody (HPAB-0194CQ) | ELISA, IHC, FC, FuncS | Human IgG2, κ |
| MOB-377YC | Human Anti-HAVCR1 Recombinant Antibody (Clone 2.70.2) | ELISA, FC, IHC | Human IgG1 kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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