CytoStream™ Mouse Anti-HAVCR2 Recombinant Antibody (VS13-YC497) (CAT#: VS13-YC497)
The CytoStream™ Mouse Anti-HAVCR2 Recombinant Antibody is specific for human HAVCR2. HAVCR2 belongs to the immunoglobulin superfamily and the TIM protein family. It's a Th1-specific cell surface protein that regulates macrophage activation, inhibits Th1-mediated autoimmune responses, and promotes immunological tolerance, dividing CD4-positive T helper lymphocytes into Th1 and Th2 types. The anti-HAVCR2 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_B_9_5.jpg
(Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_B_9_5.jpg
Figure 2 Colon
(Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_9_3.jpg
(Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_9_3.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_9_5.jpg
Figure 4 Testis
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_5_6.jpg
(Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_5_6.jpg
Figure 5 High expression in lymph node.
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_8_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, Daudi, HDLM-2, HMC-1, RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135077-HAVCR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135077-HAVCR2
Specifications
- Immunogen
- Recombinant human Tim3, aa 1-89.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human HAVCR2
- Species Reactivity
- Human
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Atopic and allergic disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 50% Glycerol and 0.2% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunofluorescence (IF-cell): 1/50-1/200
Immunohistochemistry-paraffin (IHC-P): 1/1000-1/5000
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Hepatitis A Virus Cellular Receptor 2; T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3; T-Cell Immunoglobulin Mucin Family Member 3; T-Cell Immunoglobulin Mucin Receptor 3; T-Cell Membrane Protein 3; HAVcr-2; TIMD-3; Tim-3;
- Gene ID
- 84868
- UniProt ID
- Q8TDQ0
- Long Name
- Hepatitis A Virus Cellular Receptor 2
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-893CQ | Rat Anti-Havcr2 Recombinant Antibody (clone B8.2C12) | Block, FC | Rat IgG1 |
| NEUT-894CQ | Rat Anti-Havcr2 Recombinant Antibody (clone RMT3-23) | Block, FC | Rat IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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