CytoStream™ Mouse Anti-HAVCR2 Recombinant Antibody (VS13-YC497)
CAT#: VS13-YC497
The CytoStream™ Mouse Anti-HAVCR2 Recombinant Antibody is specific for human HAVCR2. HAVCR2 belongs to the immunoglobulin superfamily and the TIM protein family. It's a Th1-specific cell surface protein that regulates macrophage activation, inhibits Th1-mediated autoimmune responses, and promotes immunological tolerance, dividing CD4-positive T helper lymphocytes into Th1 and Th2 types. The anti-HAVCR2 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_9_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_5_6.jpg
Normal Tissue
Figure 5 High expression in lymph node.
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/26003/54545_A_8_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, Daudi, HDLM-2, HMC-1, RPMI-8226)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000135077-HAVCR2
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Specifications
- Immunogen
- Recombinant human Tim3, aa 1-89.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human HAVCR2
- Species Reactivity
- Human
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Atopic and allergic disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 50% Glycerol and 0.2% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunofluorescence (IF-cell): 1/50-1/200
Immunohistochemistry-paraffin (IHC-P): 1/1000-1/5000
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Hepatitis A Virus Cellular Receptor 2; T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3; T-Cell Immunoglobulin Mucin Family Member 3; T-Cell Immunoglobulin Mucin Receptor 3; T-Cell Membrane Protein 3; HAVcr-2; TIMD-3; Tim-3;
- Gene ID
- 84868
- UniProt ID
- Q8TDQ0
- Long Name
- Hepatitis A Virus Cellular Receptor 2
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| MOR-4214 | Rabbit Anti-HAVCR2 Recombinant Antibody (clone SI293DS) | ELISA | Rabbit IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0506-CN | Mouse Anti-HAVCR2 Recombinant Antibody (HPAB-0506-CN) | ELISA, FC | Mouse IgG |
| HPAB-0507-CN | Mouse Anti-HAVCR2 Recombinant Antibody (HPAB-0507-CN) | ELISA, FC | Mouse IgG |
| HPAB-0508-CN | Mouse Anti-HAVCR2 Recombinant Antibody (HPAB-0508-CN) | ELISA, FC | Mouse IgG |
| HPAB-0509-CN | Human Anti-HAVCR2 Recombinant Antibody (HPAB-0509-CN) | ELISA, FC | Chimeric (mouse/human) IgG1, κ |
| HPAB-0510-CN | Human Anti-HAVCR2 Recombinant Antibody (HPAB-0510-CN) | ELISA, FC | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0351-YC-F(E) | Human Anti-HAVCR2 Recombinant Antibody (clone NOV020YC); Fab Fragment | FC, ELISA | Human Fab |
| HPAB-1047LY-F(E) | Human Anti-HAVCR2 Recombinant Antibody; Fab Fragment (HPAB-1047LY-F(E)) | ELISA | Human Fab |
| HPAB-1048LY-F(E) | Human Anti-HAVCR2 Recombinant Antibody; Fab Fragment (HPAB-1048LY-F(E)) | ELISA | Human Fab |
| HPAB-1049LY-F(E) | Human Anti-HAVCR2 Recombinant Antibody; Fab Fragment (HPAB-1049LY-F(E)) | ELISA | Human Fab |
| HPAB-1050LY-F(E) | Human Anti-HAVCR2 Recombinant Antibody; Fab Fragment (HPAB-1050LY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1047LY-S(P) | Human Anti-HAVCR2 Recombinant Antibody; scFv Fragment (HPAB-1047LY-S(P)) | ELISA | Human scfv |
| HPAB-1048LY-S(P) | Human Anti-HAVCR2 Recombinant Antibody; scFv Fragment (HPAB-1048LY-S(P)) | ELISA | Human scfv |
| HPAB-1049LY-S(P) | Human Anti-HAVCR2 Recombinant Antibody; scFv Fragment (HPAB-1049LY-S(P)) | ELISA | Human scfv |
| HPAB-1050LY-S(P) | Human Anti-HAVCR2 Recombinant Antibody; scFv Fragment (HPAB-1050LY-S(P)) | ELISA | Human scfv |
| HPAB-1051LY-S(P) | Human Anti-HAVCR2 Recombinant Antibody; scFv Fragment (HPAB-1051LY-S(P)) | ELISA | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1520 | Human Anti-HAVCR2 Recombinant Antibody (clone TSR-022) | ELISA, FC | Humanized IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY30 | Rat Anti-HAVCR2 Agonistic Antibody (VS-0724-XY30) | Agonistic assays | Rat IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY117 | CytoStream™ Rat Anti-HAVCR2 Recombinant Antibody (VS-0225-XY117) | FC | Rat IgG2a, kappa |
| VS-0225-XY118 | CytoStream™ Mouse Anti-HAVCR2 Recombinant Antibody (VS-0225-XY118) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY3 | Human Anti-HAVCR2 scFv-Fc Chimera (VS-0325-FY3) | ELISA, FC | Human IgG1, scFv-Fc |
| VS-0325-FY125 | Mouse Anti-HAVCR2 (clone mAb15) scFv-Fc Chimera | FC, Block, ELISA, FuncS | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC542 | Recombinant Anti-HAVCR2 Vesicular Antibody, EV Displayed (VS-0425-YC542) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3062 | Anti-HAVCR2 Immunohistochemistry Kit | IHC |
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