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    Mouse Anti-HDAC2 Recombinant Antibody (clone 4D8C3) (CAT#: VS7-0425-WR21)

    This product is a mouse IgG1 recombinant antibody that binds to human HDAC2. 4D8C3 recognizes the specific domains AA: 217-327 on human HDAC2. This antibody can be used for WB, IHC, and FC assays. It also cross reacts with mouse, monkey, and rat.

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    • Purity:

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    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11727/if_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/if_selected.jpg
    Normal Tissue
    Figure 3 IHC staining of human hippocampus
    Figure 3 IHC staining of human hippocampus
    (Immunohistochemical staining of human hippocampus shows strong nuclear positivity in neuronal cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/ihc_selected.jpg
    Figure 4 Lymph node
    Figure 4 Lymph node
    (Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_A_8_8.jpg
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_B_7_5.jpg
    Figure 6 Salivary gland
    Figure 6 Salivary gland
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_B_2_1.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_A_9_5.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196591-HDAC2

    Specifications

    • Immunogen
    • Recombinant human HDAC2 (AA: 217-327) fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human HDAC2
    • Species Reactivity
    • Human, Mouse, Monkey, Rat
    • Clone
    • 4D8C3
    • Molecule Class
    • Enzyme
    • Applications
    • WB, IHC, FC
    • Conjugate
    • Unconjugated
    • Related Disease
    • Neurodegenerative Diseases; Cancer; Psychiatric Disorders; Cardiovascular Diseases; Inflammatory Diseases; Metabolic Diseases

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • 0.05% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry-Paraffin: 1:200 - 1:1000
      Flow Cytometry: 1:200 - 1:400
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • HD2; RPD3; YAF1; KDAC2
    • Long Name
    • Histone deacetylase 2
    • Cellular Localization
    • Cytoplasm; Nucleus
    • Post Translation Modifications
    • Acetylation; Isopeptide bond; Phosphoprotein; S-nitrosylation; Ubl conjugation
    • Function
    • Chromatin regulator; Hydrolase; Repressor

    Recommended Products

    Isotype Control

    Secondary Antibody

    Reconstitution Buffer

    Recommended Dilution Buffer

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "HDAC2"

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    IgG Antibody Products Rabbit Monoclonal Antibody Products Antibody Magnetic Beads IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    MOB-3737z Mouse Anti-HDAC2 Recombinant Antibody (clone 31B12) WB, IP, IF, IHC Mouse IgG2b, κ
    MOB-2296CT Recombinant Mouse anti-Human HDAC2 Monoclonal antibody (FQS5045) IHC-P, WB, IP, ChIP, ICC/IF
    VS3-WK1085 Mouse Anti-HDAC2 Recombinant Antibody (VS3-WK1085) WB Mouse IgG1
    VS3-WK1086 Rabbit Anti-HDAC2 Recombinant Antibody (VS3-WK1086) WB, ICC, IF, IHC, IP, FC Rabbit IgG
    VS3-FY2733 Mouse Anti-HDAC2 Recombinant Antibody (VS3-FY2733) WB, ICC Mouse IgG

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