Mouse Anti-HTR3A Recombinant Antibody (clone 3B11C10) (CAT#: VS7-0425-WR101)
This product is a mouse IgG2a recombinant antibody that binds to human HTR3A. The antibody 3B11C10 recognizes a specific amino acid domain of human HTR3A (AA: extra 24-157). It can be used for IHC, ICC, and FC assays.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in a subset of non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in a subset of non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8_selected.jpg
Figure 2 Kidney
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_7_5.jpg
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_7_5.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, NTERA-2, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166736-HTR3A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166736-HTR3A
Specifications
- Immunogen
- Recombinant human HTR3A (AA: extra 24-157) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human HTR3A
- Species Reactivity
- Human
- Clone
- 3B11C10
- Molecule Class
- Ligand-Gated Ion Channel Receptor Superfamily
- Applications
- IHC, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Nausea and Vomiting; Irritable Bowel Syndrome (IBS); Anxiety and Mood Disorders; Pain Perception; Substance Use Disorders
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Immunocytochemistry: 1:100 - 1:500
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R
- Gene ID
- 3359
- UniProt ID
- P46098
- Long Name
- 5-hydroxytryptamine receptor 3A
- Cellular Localization
- Cell membrane; Membrane; Postsynaptic cell membrane; Synapse
- Post Translation Modifications
- Disulfide bond; Glycoprotein
- Protein Refseq
- NP_000860.3
- Function
- Ion channel; Ligand-gated ion channel; Receptor
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2699z | Mouse Anti-HTR3A Recombinant Antibody (clone 43A2) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2a |
| VS7-0425-WR102 | Mouse Anti-HTR3A Recombinant Antibody (clone 4D5E7) | IHC, ICC, FC | Mouse IgG2a |
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