Mouse Anti-HTR3A Recombinant Antibody (clone 4D5E7) (CAT#: VS7-0425-WR102)
This product is a mouse IgG2a recombinant antibody that binds to human HTR3A. The antibody 4D5E7 recognizes a specific amino acid domain of human HTR3A (AA: extra 24-157). It can be used for IHC, ICC, and FC assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human lymph node
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in a subset of non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8_selected.jpg
(Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in a subset of non-germinal center cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8_selected.jpg
Figure 2 Kidney
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_7_5.jpg
(Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_7_5.jpg
Figure 3 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69442/162965_A_8_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, NTERA-2, SCLC-21H)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166736-HTR3A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000166736-HTR3A
Specifications
- Immunogen
- Recombinant human HTR3A (AA: extra 24-157) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human HTR3A
- Species Reactivity
- Human
- Clone
- 4D5E7
- Molecule Class
- Ligand-Gated Ion Channel Receptor Superfamily
- Applications
- IHC, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Nausea and Vomiting; Irritable Bowel Syndrome (IBS); Anxiety and Mood Disorders; Pain Perception; Substance Use Disorders
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Immunocytochemistry: 1:100 - 1:500
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R
- Gene ID
- 3359
- UniProt ID
- P46098
- Long Name
- 5-hydroxytryptamine receptor 3A
- Cellular Localization
- Cell membrane; Membrane; Postsynaptic cell membrane; Synapse
- Post Translation Modifications
- Disulfide bond; Glycoprotein
- Protein Refseq
- NP_000860.3
- Function
- Ion channel; Ligand-gated ion channel; Receptor
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Single Domain Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2699z | Mouse Anti-HTR3A Recombinant Antibody (clone 43A2) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG2a |
| VS7-0425-WR101 | Mouse Anti-HTR3A Recombinant Antibody (clone 3B11C10) | IHC, ICC, FC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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