Recombinant Human Anti-IAV HA Antibody (1C4) (CAT#: HPAB-0116-WJ)
This product is a human IgG1 kappa antibody targeting hemagglutinin (HA) of influenza A virus. This antibody can be combined with HA2 subunit of influenza virus hemagglutinin (HA) with native conformation, and can prevent multiple influenza virus subtypes from infecting permissive cells.
Specific Inquiry
WB
Figure 1 Western blot analysis of the generated HA pseudovirus.
Pseudoviruses(50 ng/ml p24) were, respectively, detected by mAbs (1:1000) specific for IAV HA.
Du, L., Zhao, G., Zhang, X., Liu, Z., Yu, H., Zheng, B. J., ... & Jiang, S. (2010). Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochemical and biophysical research communications, 397(3), 580-585.
Neut
Figure 2 Pseudovirus neutralization detec-tion of HA-specific mAbs against infection of HA pseudovirus in 293T cell.
The experiment was repeated three times and similar results were obtained.L. Du et al./Biochemical and Biophysical Research Communications 397 (2010) 580–585583
Du, L., Zhao, G., Zhang, X., Liu, Z., Yu, H., Zheng, B. J., ... & Jiang, S. (2010). Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochemical and biophysical research communications, 397(3), 580-585.
ELISA
Figure 3 ELISA detection of IgG response of 20 screened mAbs specific to HA.
The data areexpressed as absorbance at 450 nm (A450).
Du, L., Zhao, G., Zhang, X., Liu, Z., Yu, H., Zheng, B. J., ... & Jiang, S. (2010). Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochemical and biophysical research communications, 397(3), 580-585.
Specifications
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- Influenza A virus HA
- Species Reactivity
- Influenza A virus
- Clone
- 1C4
- Applications
- Neut, WB, ELISA
- Related Disease
- Influenza
Applications
- Application Notes
- The IAV HA antibody has been reported in applications of Western Blot, Neutralization, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Influenza A Hemagglutinin; Influenza A; H1N1; Group V ((-)ssRNA); Orthomyxoviridae; S-OIV A Hemagglutinin; Swine flu H1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-078 | Recombinant Anti-IAV HA VHH Single Domain Antibody | FC, CA, IP, FuncS | Llama VHH |
| HPAB-0344CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (HPAB-0344CQ) | ELISA, Neut | Llama VHH |
| HPAB-0345CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (HPAB-0345CQ) | ELISA, Neut | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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