Recombinant Human Anti-IAV HA Antibody (1C4) (CAT#: HPAB-0116-WJ)
This product is a human IgG1 kappa antibody targeting hemagglutinin (HA) of influenza A virus. This antibody can be combined with HA2 subunit of influenza virus hemagglutinin (HA) with native conformation, and can prevent multiple influenza virus subtypes from infecting permissive cells.
Specific Inquiry
WB
Figure 1 Western blot analysis of the generated HA pseudovirus.
Pseudoviruses(50 ng/ml p24) were, respectively, detected by mAbs (1:1000) specific for IAV HA.
Du, L., Zhao, G., Zhang, X., Liu, Z., Yu, H., Zheng, B. J., ... & Jiang, S. (2010). Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochemical and biophysical research communications, 397(3), 580-585.
Neut
Figure 2 Pseudovirus neutralization detec-tion of HA-specific mAbs against infection of HA pseudovirus in 293T cell.
The experiment was repeated three times and similar results were obtained.L. Du et al./Biochemical and Biophysical Research Communications 397 (2010) 580–585583
Du, L., Zhao, G., Zhang, X., Liu, Z., Yu, H., Zheng, B. J., ... & Jiang, S. (2010). Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochemical and biophysical research communications, 397(3), 580-585.
ELISA
Figure 3 ELISA detection of IgG response of 20 screened mAbs specific to HA.
The data areexpressed as absorbance at 450 nm (A450).
Du, L., Zhao, G., Zhang, X., Liu, Z., Yu, H., Zheng, B. J., ... & Jiang, S. (2010). Development of a safe and convenient neutralization assay for rapid screening of influenza HA-specific neutralizing monoclonal antibodies. Biochemical and biophysical research communications, 397(3), 580-585.
Specifications
- Host Species
- Human
- Type
- Human IgG1, κ
- Specificity
- Influenza A virus HA
- Species Reactivity
- Influenza A virus
- Clone
- 1C4
- Applications
- Neut, WB, ELISA
- Related Disease
- Influenza
Applications
- Application Notes
- The IAV HA antibody has been reported in applications of Western Blot, Neutralization, Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Influenza A Hemagglutinin; Influenza A; H1N1; Group V ((-)ssRNA); Orthomyxoviridae; S-OIV A Hemagglutinin; Swine flu H1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 1C4"
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-078 | Recombinant Anti-IAV HA VHH Single Domain Antibody | FC, CA, IP, FuncS | Llama VHH |
| HPAB-0344CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (SD38) | ELISA, Neut | Llama VHH |
| HPAB-0345CQ | Recombinant Llama Anti-IAV HA Single Domain Antibody (SD36) | ELISA, Neut | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H33 | Anti-IAV HA Recombinant Antibody (Firivumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
| TAB-027ML | Anti-IAV HA Recombinant Antibody (Gedivumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
| TAB-438CQ | Anti-IAV HA Recombinant Antibody (Navivumab) | ELISA, IHC, FC, IP, IF, BL | IgG1, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABZ-077 | Recombinant Mouse Anti-IAV HA Antibody (BH151) | Neut | IgG |
| PABW-077 | Recombinant Mouse Anti-IAV HA Antibody (HC19) | Neut | IgG |
| PABC-488 | Recombinant Human Anti-IAV HA Antibody (27F3) | ELISA, Neut | Human IgG1, κ |
| PABC-489 | Recombinant Human Anti-IAV HA Antibody (31.a.83) | Neut | Human IgG1, κ |
| HPAB-612-FY | Human Anti-IAV HA Recombinant Antibody (HPAB-612-FY) | Inhib | Human IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-483 | Human Anti-IAV HA Recombinant Antibody; Fab Fragment (PFBL-483) | Neut | Human Fab |
| PFBC-343 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (6639) | ELISA, Neut | Human Fab |
| PFBC-344 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (56.a.09) | ELISA, FC, Neut | Human Fab |
| PFBC-345 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (31.b.09) | ELISA, FC, Neut | Human Fab |
| PFBC-346 | Recombinant Human Anti-IAV HA Antibody Fab Fragment (16.a.26) | ELISA, FC, Neut | Human Fab |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0652CQ | Recombinant Mouse Anti-IAV HA Antibody (pSAN13.4.1) | ELISA | IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-027ML | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Gedivumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-438CQ | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Navivumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
| AFC-TAB-H33 | Afuco™ Anti-IAV HA ADCC Recombinant Antibody (Firivumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0304-WJ-S(P) | Human Anti-IAV HA Recombinant Antibody; scFv Fragment (HPAB-0304-WJ-S(P)) | Neut | Human scFv |
| HPAB-0878-FY-F(E) | Recombinant Anti-IAV HA Antibody scFv Fragment (TCN-504 (3251_K17)) | N | |
| PABJ-0096-S(P) | Mouse Anti-IAV HA Recombinant Antibody (clone 8H10); scFv Fragment | ELISA, FuncS | Mouse scFv |
| PABJ-0130-S(P) | Human Anti-IAV HA Recombinant Antibody (clone CH67:1203d4); scFv Fragment | ELISA, Inhib | Human scFv |
| PABJ-0131-S(P) | Human Anti-IAV HA Recombinant Antibody (clone CH65:7969d2); scFv Fragment | ELISA, Inhib | Human scFv |
MHC Tetramer for Virology
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YC213 | H-2Kd/Influenza A virus Haemagglutinin (IYSTVASSL) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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