Recombinant Human Anti-IAV HA Antibody (3C4) (CAT#: HPAB-0118-WJ)

This product is a human IgG1 kappa antibody targeting hemagglutinin (HA) of influenza A virus. This antibody is capable of binding to influenza virus hemagglutinin protein (HA) of the native conformation of the HA2 subunit, multiple subtypes of influenza can be prevented virus infection of susceptible cells.

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FuncS

Figure 1 HA inhibitory MoAbs on the ability of the virus to cause neutrophil deactivation.

Figure 1 HA inhibitory MoAbs on the ability of the virus to cause neutrophil deactivation.

All results shown are the mean SEM of 3 or more experiments.

Hartshorn, K. L., Reid, K. B., White, M. R., Jensenius, J. C., Morris, S. M., Tauber, A. I., & Crouch, E. (1996). Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies.

Inhib

Figure 2 Effect of incubating IAV with HA inhibiting MoAbs, RhSPD multimers, or GST-SP-DICRD on neutrophil binding of the virus.

Figure 2 Effect of incubating IAV with HA inhibiting MoAbs, RhSPD multimers, or GST-SP-DICRD on neutrophil binding of the virus.

All results shown are the mean SEM of 3 or more experiments.

Hartshorn, K. L., Reid, K. B., White, M. R., Jensenius, J. C., Morris, S. M., Tauber, A. I., & Crouch, E. (1996). Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies.

IHC

Figure 3 Effect of RhSP-D on IAV binding to neutrophils was assessed.

Figure 3 Effect of RhSP-D on IAV binding to neutrophils was assessed.

Results depicted are representative of more than three separate experiments.

Hartshorn, K. L., Reid, K. B., White, M. R., Jensenius, J. C., Morris, S. M., Tauber, A. I., & Crouch, E. (1996). Neutrophil deactivation by influenza A viruses: mechanisms of protection after viral opsonization with collectins and hemagglutination-inhibiting antibodies.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, κ
  • Specificity
  • Influenza A virus HA
  • Species Reactivity
  • Influenza A virus
  • Clone
  • 3C4
  • Applications
  • Used for immunoassay techniques such as: Enzyme Linked Immunosorbent Assay, Western Blot
  • Related Disease
  • Influenza

Target

  • Alternative Names
  • Influenza A Hemagglutinin; Influenza A; H1N1; Group V ((-)ssRNA); Orthomyxoviridae; S-OIV A Hemagglutinin; Swine flu H1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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