Rabbit Anti-IFNGR1 Recombinant Antibody (clone R08-9H9) (CAT#: VS3-FY1745)
Clone R08-9H9 is a rabbit recombinant monoclonal antibody that detects human IFNGR1, a 54 kDa member of the immunodlobulin superfamily. It cross-reacts with mouse, rat. This antbody has been tested by western blot analysis of IFNGR1 in K562, C6, 3T3, Hela lysates.
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WB
Figure 1 Anti-IFNGR1 Antibody (VS3-FY1745) in WB.
The IFNGR1 expression in K562, C6, 3T3, Hela lysates were detected using the anti-Interferon gamma Receptor 1 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human IFNGR1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat IFNGR1
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R08-9H9
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 54 kDa, while the observed molecular weight stands at 100 kDa.
- Related Disease
- Mycobacterial disease
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Interferon Gamma Receptor 1
- Gene ID
- 3459
- UniProt ID
- P15260
- Sequence Similarities
- Belongs to the type II cytokine receptor family.
- Cellular Localization
- Cell membrane, Membrane
- Post Translation Modifications
- Phosphorylated at Ser/Thr residues. Phosphorylation of Tyr-457 is required for IFNG receptor signal transduction (PubMed:8156998).
Influenza virus infection leads to phosphorylation in a CSNK1A1-dependent manner (PubMed:29343571).4 Publications
Ubiquitinated after phosphorylation in a CSNK1A1-dependent manner, leading to the lysosome-dependent degradation (PubMed:29343571).
Proteasomally degraded through 'Lys-48'-mediated ubiquitination (PubMed:28883123).
Ubiquitination is necessary for efficient IFNGR1 signaling (PubMed:28883123).
- Protein Refseq
- XP_006715533.1; XP_011534095.1; XP_011534096.1; XP_047274682.1; XP_054211301.1
- Function
- Receptor subunit for interferon gamma/INFG that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1758z | Mouse Anti-IFNGR1 Recombinant Antibody (clone 22B6) | WB, ELISA, FC, IHC | Mouse IgG2a |
| FAMAB-0193CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R38) | ELISA, RIA | Mouse IgG |
| FAMAB-0194CQ | Mouse Anti-IFNGR1 Recombinant Antibody (clone gamma R99) | ELISA, RIA | Mouse IgG |
| FAMAB-1381CQ | Rabbit Anti-IFNGR1 Recombinant Antibody (clone GR20) | Block, Neut, FC | Rabbit IgG |
| VS3-FY729 | Recombinant Mouse Anti-IFNGR1 Antibody (clone 3B2D4) | ELISA, ICC, FC | Mouse IgG2b |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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