Mouse Anti-IL1A Recombinant Antibody (clone 3D12.E3) (CAT#: VS-0724-XY83)
This product is a recombinant mouse antibody binding to human IL1A. It was obtained by immunizing Balb/c mice with recombinant IL1A protein (rhIL1A). The antibody has high affinity against human IL1A and the KD value of this antibody against human IL1A is 1.11 nM.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Group enriched (HBEC3-KT, hTCEpi, hTERT-HME1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115008-IL1A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000115008-IL1A
Specifications
- Immunogen
- Purified recombinant human IL-1α
- Host Species
- Mouse
- Derivation
- Hybridoma
- Type
- Human IgG
- Specificity
- IL1A
- Species Reactivity
- Human
- Clone
- 3D12.E3
- Applications
- ELISA, BLI, Neut
- Related Disease
- Cholesteatoma of Middle Ear; Keratoconjunctivitis Sicca
Product Property
- Purification
- Protein G affinity purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- BLI: The KD value of 3D12.E3 agaisnt IL1A is 1.11 nM.
Target
- Alternative Names
- IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha
- Gene ID
- 3552
- UniProt ID
- P01583
- Cellular Localization
- Nucleus; Cytoplasm
- Post Translation Modifications
- Glycosylation at Asn102 and Asn141.
- Protein Refseq
- NP_000566.3; NP_001358483.1
- Function
- Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems.
After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-094 | Recombinant Anti-human IL1A VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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