AibGenesis™ Rabbit Anti-IL1RN Recombinant Antibody (AibG-Rb-L1214)
CAT#: VS14-YC415
Leveraging our deep learning discovery platform, this antibody is crafted for high-affinity recognition of IL1RN in mammalian samples. IL1RN is a natural antagonist of the Interleukin-1 receptor that competitive inhibits IL-1 binding. It is a key negative regulator of the IL-1 mediated inflammatory signaling pathway, protecting tissues from excessive cytokine-induced damage.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to nucleoplasm, cytosol & centrosome.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/1422_G7_6_selected.jpg
Normal Tissue
Figure 2 High expression in esophagus
Squamous epithelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/4971_B_5_1.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1482/4626_A_9_5.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (A-431, HaCaT, RT4, THP-1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000136689-IL1RN
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Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- IL1RN
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-L1214
- Applications
- Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC)
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% Glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (WB): 1/5000-1/20000
Immunohistochemistry (IHC): 1/50-1/200
Immunocytochemistry (ICC): 1/50-1/200
Flow Cytometry (FC): 1/50
Immunoprecipitation (IP): 1/50
Target
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "IL1RN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1402z | Mouse Anti-IL1RN Recombinant Antibody (clone 8C2) | WB, IHC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0238CT | Recombinant Mouse anti-Human IL1RN Monoclonal antibody (B82C7E22) | ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1305CQ | Mouse Anti-IL1RN Recombinant Antibody (clone CBL417) | ELISA, Neut | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1800 | Rabbit Anti-IL1RN Recombinant Antibody (clone DS1800AB) | WB, IHC, ICC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1749 | Rabbit Anti-IL1RN Recombinant Antibody (clone R01-6J5) | WB, IHC-Fr, IHC-P, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1726 | Recombinant Rabbit Anti-IL1RN Capture Antibody (clone R02-6W5) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1727 | Recombinant Rabbit Anti-IL1RN Detection Antibody (clone R05-7M2) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3509 | Anti-IL1RN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3510 | Anti-Mouse IL1RN Immunohistochemistry Kit | IHC |
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