Afuco™ Anti-IL31 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-419CQ)
CAT#: AFC-TAB-419CQ
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL31. It is a caninized monoclonal antibody that can be potentially used in the treatment of Canine atopic dermatitis (AD).
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_7_5.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_7_5.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_8_8.jpg
Normal Tissue
Figure 4 Spleen
Cells in red pulp
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_9_4.jpg
RNA Expression
Figure 5 RNA cell line category: Not detected
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204671-IL31
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Canine
- Derivation
- Caninized
- Type
- ADCC enhanced antibody
- Specificity
- Canine IL31
- Species Reactivity
- Canine
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Lokivetmab
- Related Disease
- Canine atopic dermatitis (AD)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Lokivetmab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lokivetmab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "IL31"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1474-sdAb | Recombinant Anti-Human IL31 VHH Single Domain Antibody | ICC, ChiP, FC, FA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1385CQ | Mouse Anti-IL31 Recombinant Antibody (VMC200) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4266 | Rabbit Anti-Il31 Recombinant Antibody (clone SI348DS) | ELISA | Rabbit IgG |
| MOR-4617 | Rabbit Anti-IL31 Recombinant Antibody (clone TH130DS) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CQ | Anti-Canine IL31 Recombinant Antibody (TAB-419CQ) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0131-LSX) | ELISA, WB | Mouse IgG |
| HPAB-0132-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0132-LSX) | ELISA, WB, Inhib | Mouse IgG |
| HPAB-0133-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0133-LSX) | ELISA, WB | Mouse IgG |
| HPAB-0134-LSX | Canine Anti-IL31 Recombinant Antibody (HPAB-0134-LSX) | ELISA, WB | Canine IgG |
| HPAB-0135-LSX | Canine Anti-IL31 Recombinant Antibody (HPAB-0135-LSX) | ELISA, WB | Canine IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0131-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0132-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0132-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0133-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0133-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0134-LSX-S(P) | Canine Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0134-LSX-S(P)) | ELISA, WB | Canine scFv |
| HPAB-0135-LSX-S(P) | Canine Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0135-LSX-S(P)) | ELISA, WB | Canine scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0131-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0132-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0132-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0133-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0133-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0134-LSX-F(E) | Canine Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0134-LSX-F(E)) | ELISA, WB | Canine Fab |
| HPAB-0135-LSX-F(E) | Canine Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0135-LSX-F(E)) | ELISA, WB | Canine Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY57 | Canine Anti-IL31 scFv-Fc Chimera (VS-0425-FY57) | ELISA | Canine IgG2, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3526 | Anti-IL31 Immunohistochemistry Kit | IHC |
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