Afuco™ Anti-IL31 ADCC Recombinant Antibody (Lokivetmab), ADCC Enhanced (CAT#: AFC-TAB-419CQ)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL31. Lokivetmab is a caninized monoclonal antibody that can be potentially used in the treatment of Canine atopic dermatitis (AD).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_7_5.jpg
(Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_7_5.jpg
Figure 2 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_7_5.jpg
(Cells in glomeruli
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_7_5.jpg
Figure 3 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_8_8.jpg
(Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_A_8_8.jpg
Figure 4 Spleen
(Cells in red pulp
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_9_4.jpg
(Cells in red pulp
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25657/60049_B_9_4.jpg
Figure 5 RNA cell line category: Not detected
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204671-IL31
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204671-IL31
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Canine
- Derivation
- Caninized
- Type
- ADCC enhanced antibody
- Specificity
- Canine IL31
- Species Reactivity
- Canine
- Clone
- Lokivetmab
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Lokivetmab
- Related Disease
- Canine atopic dermatitis (AD)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Please refer to Lokivetmab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lokivetmab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Lokivetmab"
Anti-Canine IL31 Recombinant Antibody (Lokivetmab)Recombinant monoclonal antibody to IL31. Lokivetmab is a caninized monoclonal antibody that can be potentially used in the treatment of Canine atopic dermatitis (AD).
See other products for "IL31"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1474-sdAb | Recombinant Anti-Human IL31 VHH Single Domain Antibody | ICC, ChiP, FC, FA | Llama VHH |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1385CQ | Mouse Anti-IL31 Recombinant Antibody (VMC200) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4266 | Rabbit Anti-Il31 Recombinant Antibody (clone SI348DS) | ELISA | Rabbit IgG |
| MOR-4617 | Rabbit Anti-IL31 Recombinant Antibody (clone TH130DS) | WB | Rabbit IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-419CQ | Anti-Canine IL31 Recombinant Antibody (Lokivetmab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0131-LSX) | ELISA, WB | Mouse IgG |
| HPAB-0132-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0132-LSX) | ELISA, WB, Inhib | Mouse IgG |
| HPAB-0133-LSX | Mouse Anti-IL31 Recombinant Antibody (HPAB-0133-LSX) | ELISA, WB | Mouse IgG |
| HPAB-0134-LSX | Canine Anti-IL31 Recombinant Antibody (HPAB-0134-LSX) | ELISA, WB | Canine IgG |
| HPAB-0135-LSX | Canine Anti-IL31 Recombinant Antibody (HPAB-0135-LSX) | ELISA, WB | Canine IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0131-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0132-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0132-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0133-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0133-LSX-S(P)) | ELISA, WB | Mouse scFv |
| HPAB-0139-LSX-S(P) | Rat Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0139-LSX-S(P)) | ELISA | Rat scFv |
| HPAB-0140-LSX-S(P) | Mouse Anti-IL31 Recombinant Antibody; scFv Fragment (HPAB-0140-LSX-S(P)) | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0131-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0131-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0132-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0132-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0133-LSX-F(E) | Mouse Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0133-LSX-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0134-LSX-F(E) | Canine Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0134-LSX-F(E)) | ELISA, WB | Canine Fab |
| HPAB-0135-LSX-F(E) | Canine Anti-IL31 Recombinant Antibody; Fab Fragment (HPAB-0135-LSX-F(E)) | ELISA, WB | Canine Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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