Afuco™ Anti-IL5RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-222) (CAT#: AFC-TAB-222)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL5RA. It is a monoclonal antibody for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091181-IL5RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000091181-IL5RA
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Benralizumab
- Related Disease
- Asthma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL5RA; interleukin 5 receptor, alpha; IL5R; interleukin-5 receptor subunit alpha; CD125; CDw125; CD125 antigen; IL-5R subunit alpha; IL-5 receptor subunit alpha; interleukin 5 receptor type 3;
- Gene ID
- 3568
- UniProt ID
- Q01344
Related Resources
Please refer to Benralizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Benralizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Benralizumab"
DrugMonitor™ Anti-Benralizumab Antibody (VS-1224-YC182)Benralizumab is a humanized recombinant monoclonal antibody binding specifically to the IL-5 receptor (IL-5R) alpha chain, approved for treating severe asthma and eosinophilic granulomatosis with polyangiitis (EGPA). The DrugMonitor™ Anti-Benralizumab Antibody (VS-1224-YC182) is an anti-drug antibody (ADA) against Benralizumab. This drug-based antibody is raised in mice immunized with the Benralizumab. The anti-Benralizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Benralizumab in samples.
See other products for "IL5RA"
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IgG Antibody Products
Humanized Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2473z | Mouse Anti-IL5RA Recombinant Antibody (clone 33H12) | WB, FC | Mouse IgG1 |
| HPAB-1545WJ | Human Anti-IL5RA Recombinant Antibody (clone KM1399) | ELISA, WB | Human IgG1, κ |
| VS-0723-WK142 | Human Anti-IL5RA Recombinant Antibody (VS-0723-WK142) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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