Afuco™ Anti-IL5RA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-222)

CAT#: AFC-TAB-222

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL5RA. It is a monoclonal antibody for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).

Gene Expression
Figure 1 RNA cell line category: Cell line enriched (HMC-1)

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • FC, IP, ELISA, Neut, FuncS
  • Conjugate
  • Unconjugated
  • Generic Name
  • Benralizumab
  • Related Disease
  • Asthma

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • IL5RA; interleukin 5 receptor, alpha; IL5R; interleukin-5 receptor subunit alpha; CD125; CDw125; CD125 antigen; IL-5R subunit alpha; IL-5 receptor subunit alpha; interleukin 5 receptor type 3;
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Biosimilar Overview

Please refer to Benralizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Benralizumab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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COA

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See other products for "Benralizumab"

DrugMonitor™ Anti-Benralizumab Antibody (VS-1224-YC182)
Benralizumab is a humanized recombinant monoclonal antibody binding specifically to the IL-5 receptor (IL-5R) alpha chain, approved for treating severe asthma and eosinophilic granulomatosis with polyangiitis (EGPA). The DrugMonitor™ Anti-Benralizumab Antibody (VS-1224-YC182) is an anti-drug antibody (ADA) against Benralizumab. This drug-based antibody is raised in mice immunized with the Benralizumab. The anti-Benralizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Benralizumab in samples.

See other products for "IL5RA"

Select a product category from the dropdown menu below to view related products.

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TAB-222 Anti-Human IL5RA Recombinant Antibody (TAB-222) WB, FC, IP, ELISA, Neut, FuncS, IF IgG1 - kappa
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MOR-1813 Rabbit Anti-IL5RA Recombinant Antibody (clone DS1813AB) WB Rabbit IgG
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HPAB-1545WJ-F(E) Human Anti-IL5RA Recombinant Antibody; Fab Fragment (clone KM1399) ELISA, WB Human Fab
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HPAB-1545WJ-S(P) Human Anti-IL5RA Recombinant Antibody; scFv Fragment (clone KM1399) ELISA, WB Human scFv
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VS-0425-FY76 Human Anti-IL5RA (clone KM1399) scFv-Fc Chimera ELISA, Inhib, IP Human IgG1, scFv-Fc
CAT Product Name Application Type
VS-0425-YC205 Recombinant Anti-IL5RA Vesicular Antibody, EV Displayed (VS-0425-YC205) ELISA, FC, Neut, Cell-uptake
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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