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Mouse Anti-LMNA Recombinant Antibody (clone 131C3) (CAT#: ZG-0958F)

This product is a mouse antibody that recognizes LMNA.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line PC-3
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6523/1905_E12_1_selected.jpg
Figure 2 IHC staining of human epididymis
Figure 2 IHC staining of human epididymis
(Immunohistochemical staining of human epididymis shows strong nuclear membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6660/ihc_selected.jpg
Figure 3 IHC staining of human rectum
Figure 3 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong nuclear membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_B_8_5.jpg
Figure 5 Colon
Figure 5 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Fibroblasts
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_9_3.jpg
Figure 6 Liver
Figure 6 Liver
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_7_4.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_8_5.jpg
Figure 8 Testis
Figure 8 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peritubular cells
Staining: High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_6_6.jpg
Figure 9 Skin
Figure 9 Skin
(Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in granular layer
Staining: High
Intensity: Strong
Quantity: 75%-25%
Cells in spinous layer
Staining: High
Intensity: Strong
Quantity: 75%-25%
Endothelial cells
Staining: High
Intensity: Strong
Fibrohistiocytic cells
Staining: High
Intensity: Strong
Langerhans cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_B_9_1.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_7_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160789-LMNA

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • 131C3 reacts with an epitope located between residues 319-566 in lamin A and C.
  • Species Reactivity
  • Cow, Dog, Hamster, Human, Mouse, Rat, Sheep
  • Clone
  • 131C3
  • Applications
  • Flow Cytometry, Immunocytochemistry, Immunohistochemistry-Frozen

Product Property

  • Format
  • Liquid
  • Buffer
  • PBS, 0.1% BSA
  • Preservative
  • 0.09% Sodium azide
  • Storage
  • Store at 4°C for short term. For long term storage, store at-20°C, avoiding freeze/thaw cycles.

Target

  • Alternative Names
  • LMNA, CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1, lamin A/C, MADA, A-type lamin

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
MOB-1798z Mouse Anti-LMNA Recombinant Antibody (clone 12B7) ICC, IF, IHC Mouse IgG3
MOB-1769MZ Recombinant Mouse Anti-Human LMNA Antibody (clone KPM3) FC, ICC/IF, IHC-Fr, IHC-P, IP, WB Mouse antibody
ZG-0261C Mouse Anti-LMNA Recombinant Antibody (ZG-0261C) WB, IHC, ELISA Mouse IgG
VS3-FY850 Recombinant Rabbit Anti-LMNA Antibody (clone R06-7H5) WB, IHC-Fr, IHC-P, ICC, IF, IP Rabbit IgG
VS3-FY851 Recombinant Rabbit Anti-LMNA Antibody (clone R07-1I5) WB, IHC-Fr, IHC-P, ICC, IF Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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