AibGenesis™ Rabbit Anti-MCM7 Recombinant Antibody (AibG-Rb-MC570)
CAT#: VS-0426-FY570
Discovered via our AI-powered antibody discovery platform, this Rabbit IgG targets MCM7. Validated for WB, IHC, and FC across Human, Mouse, and Rat, it serves as a robust tool for researchers investigating the mini-chromosome maintenance complex and its role as a diagnostic indicator in various cancers.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3898/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2163/if_selected.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/if_selected.jpg
Normal Tissue
Figure 4 Tonsil
High expression in tonsil
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3898/10901_A_5_8_selected.jpg
Normal Tissue
Figure 5 Bone marrow
High expression in bone marrow
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_B_5_4_val_selected.jpg
Normal Tissue
Figure 6 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity: 75%-25% Mucosal lymphoid cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_A_8_3.jpg
Normal Tissue
Figure 7 Kidney
Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_A_9_5.jpg
Normal Tissue
Figure 8 Skin
Cells in basal layer Staining: High Intensity: Strong Quantity:>75% Cells in spinous layer Staining: Medium Intensity: Strong Quantity: <25% Endothelial cells Staining: High Intensity: Strong Fibrohistiocytic cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_B_7_1.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16312/37227_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166508-MCM7
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Specifications
- Immunogen
- Human
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MCM7
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-MC570
- Applications
- Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Immunoprecipitation
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Endometrial Carcinoma
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% Protective protein
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:500-1:2000), Immunohistochemistry (1:50-1:100), Immunocytochemistry/Immunofluorescence (1:20-1:50), Flow Cytometry (1:20-1:50), Immunoprecipitation (1:20-1:50)
Target
- Alternative Names
- MCM2; CDC47; P85MCM; P1CDC47; PNAS146; PPP1R104; P1.1-MCM3
- Gene ID
- 4176
- UniProt ID
- P33993
- Long Name
- Minichromosome Maintenance Complex Component 7
- Function
- A core component of the MCM2-7 helicase complex; it is essential for the initiation and elongation of DNA replication by unwinding the double helix at the replication fork.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "MCM7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0743CL | Mouse Anti-MCM7 Recombinant Antibody (TAB-0743CL) | ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0743CL-S(P) | Mouse Anti-MCM7 Recombinant Antibody; scFv Fragment (TAB-0743CL-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0743CL-F(E) | Mouse Anti-MCM7 Recombinant Antibody; Fab Fragment (TAB-0743CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1147CT | Recombinant Mouse anti-Human MCM7 Monoclonal antibody (EDT-252) | ICC, IF, IP, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2194 | Hi-Affi™ Recombinant Rabbit Anti-MCM7 Monoclonal Antibody (DS2194AB) | ICC, IF, WB, IP, ICC, FC, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY913 | Recombinant Rabbit Anti-MCM7 Antibody (clone R07-7A4) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1324 | Anti-MCM7 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4314 | Anti-Human MCM7 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS14-YC451 | AibGenesis™ Rabbit Anti-MCM7 Recombinant Antibody (AibG-Rb-CM7250) | WB, IHC, ICC, IF | Rabbit IgG |
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