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  • Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10); Fab Fragment

Mouse Anti-MFGE8 Recombinant Antibody (clone 3D10); Fab Fragment (CAT#: FAMAB-0365JF-F(E))

Recombinant monoclonal antibody specially binds to MFGE8 protein-bound 4-oxo-2-nonenal (ONE). 3D10 is a mouse monoclonal antibody that can play a critical role in removing multiple damage-associated molecules, including oxidation-specific epitopes and late apoptotic/necrotic cells thyroid autoimmunity.

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  • Gene Expression
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/if_selected.jpg
Figure 2 IHC staining of human placenta
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows cytoplasmic positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_1_7_selected.jpg
Normal Tissue
Figure 3 IHC staining of human endometrium
Figure 3 IHC staining of human endometrium
(High expression. RNA expression: 444.7 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_B_5_3_val_selected.jpg
Figure 4 IHC staining of human duodenum
Figure 4 IHC staining of human duodenum
(Low expression. RNA expression: 21.2 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_9_2_val_selected.jpg
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Glial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8042_B_7_5.jpg
Figure 6 Colon
Figure 6 Colon
(Enterocytes - Microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_3.jpg
Figure 7 Liver
Figure 7 Liver
(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_8_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining: High
Intensity: Strong
Quantity:>75%
Proximal tubules (microvilli)
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_5.jpg
Figure 9 Testis
Figure 9 Testis
(Cells in seminiferous ducts
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2807/8016_A_4_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2753/7591_A_7_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Figure 11 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000140545-MFGE8

Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human MFGE8
  • Species Reactivity
  • Mouse
  • Clone
  • 3D10
  • Applications
  • IB, WB, ELISA, FuncS
  • Related Disease
  • Autoimmune disease

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT Product Name Application Type
MOB-657 Recombinant Anti-human MFGE8 Antibody WB, Neut, FuncS IgG
MHH-657 Recombinant Human Anti-human MFGE8 Antibody IF, ELISA, FuncS IgG
MOB-1240MZ Recombinant Mouse Anti-Human MFGE8 Antibody (clone FEN56), Biotin-Conjugated ICC/IF, IHC-P, IP, WB Mouse antibody
FAMAB-0225CQ Mouse Anti-MFGE8 Recombinant Antibody (clone Mc3) ELISA, IF, Block, FuncS Mouse IgG1, κ
VS1-YJ106 Mouse Anti-MFGE8 Recombinant Antibody (clone MFG-06) IHC, IHC-P Mouse IgG1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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