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    Afuco™ Anti-MST1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-184) (CAT#: AFC-TAB-184)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to RON. It is a human monoclonal antibody designed for the treatment of cancer.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/44_E6_1_selected.jpg
    Normal Tissue
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_6_6.jpg
    Figure 7 Skin
    Figure 7 Skin
    (Fibroblasts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_1.jpg
    Figure 8 Lymph node
    Figure 8 Lymph node
    (Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_8_8.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
    Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164078-MST1R

    Specifications

    • Immunogen
    • RE7 cells and MDCK cells overexpressing the human RON receptor in complete Freund`s adjuvant
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • FuncS, IF, Neut, ELISA, FC, IP
    • Conjugate
    • Unconjugated
    • Generic Name
    • Narnatumab
    • Related Disease
    • Solid tumors

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • MST1R; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); PTK8, PTK8 protein tyrosine kinase 8, RON; macrophage-stimulating protein receptor; CD136; CDw136; p185-Ron; MSP receptor; RON variant E2E3

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Narnatumab"

    Anti-Human RON Recombinant Antibody (Narnatumab)
    Recombinant monoclonal antibody to RON. Narnatumab is a human monoclonal antibody designed for the treatment of cancer.

    See other products for "MST1R"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
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    CAT Product Name Application Type
    MOB-3123z Mouse Anti-MST1R Recombinant Antibody (clone 29B12) WB, IP, IF, ELISA Mouse IgG1, κ
    HPAB-0062-CN Human Anti-MST1R Recombinant Antibody (clone MOR07923) IP, ELISA, FC Human IgG
    HPAB-0063-CN Human Anti-MST1R Recombinant Antibody (clone MOR07924) IP, ELISA, FC Human IgG
    HPAB-N0183-YC Mouse Anti-MST1R Recombinant Antibody (HPAB-N0183-YC) ELISA, IF, IHC, FC, FuncS Mouse IgG
    HPAB-N0184-YC Human Anti-MST1R Recombinant Antibody (HPAB-N0184-YC) FuncS Humanized IgG1, κ

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