Afuco™ Anti-MUC5AC ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-200)
CAT#: AFC-TAB-200
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to 5AC. It is a chimeric monoclonal antibody used in the treatment of cancers.
Gene Expression
Normal Tissue
Figure 1 High expression in stomach 1
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_6_1_val_selected.jpg
Normal Tissue
Figure 2 Low expression in liver
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_9_4_val_selected.jpg
Normal Tissue
Figure 3 Stomach
Glandular cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/40615/124256_A_3_1.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (A549, OE19)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000215182-MUC5AC
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Specifications
- Immunogen
- M1 mucin preparation from the fluid of an ovarian mucinous cyst.
- Host Species
- Chimeric
- Derivation
- Chimeric (mouse/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- IP, IF, FuncS, FC, Neut, ELISA
- Conjugate
- Unconjugated
- Generic Name
- Ensituximab
- Related Disease
- Colorectal cancers
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Ensituximab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ensituximab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Ensituximab"
DrugMonitor™ Anti-Ensituximab Antibody (VS-1224-YC429)Ensituximab (NEO-102) is a novel chimeric mAb targeting a glycosylated MUC5AC variant, specific to colorectal and pancreatic cancers. The DrugMonitor™ Anti-Ensituximab Antibody (VS-1224-YC429) is an anti-drug antibody (ADA) against Ensituximab. This drug-based antibody is raised in mice immunized with the Ensituximab. The anti-Ensituximab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Ensituximab in samples.
See other products for "MUC5AC"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-200 | Anti-Human MUC5AC Recombinant Antibody (TAB-200) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-404MZ | Mouse Anti-MUC5AC Recombinant Antibody (TAB-404MZ) | ELISA, Inhib, IHC, IA | Mouse IgG |
| TAB-404MZ-S(P) | Mouse Anti-MUC5AC Recombinant Antibody; scFv Fragment (TAB-404MZ-S(P)) | IHC | Mouse scFv |
| TAB-404MZ-F(E) | Mouse Anti-MUC5AC Recombinant Antibody; Fab Fragment (TAB-404MZ-F(E)) | IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-405MZ | Human Anti-MUC5AC Recombinant Antibody (TAB-405MZ) | IF, WB, IHC, IA | Humanized IgG |
| TAB-405MZ-S(P) | Human Anti-MUC5AC Recombinant Antibody; scFv Fragment (TAB-405MZ-S(P)) | IHC | Humanized scFv |
| TAB-406MZ-S(P) | Anti-Human MUC5AC Recombinant Antibody scFv Fragment (VH-1) | FC, ELISA | Humanized antibody |
| TAB-405MZ-F(E) | Human Anti-MUC5AC Recombinant Antibody; Fab Fragment (TAB-405MZ-F(E)) | IHC | Humanized Fab |
| TAB-406MZ-F(E) | Anti-Human MUC5AC Recombinant Antibody Fab Fragment (VH-1) | FC, ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0585CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (19-O Le) | ELISA | IgM |
| EPAF-0586CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (2-25 Le) | ELISA | IgG1 |
| EPAF-0587CQ | Recombinant Mouse Anti-Human MUC5AC Antibody (7 Le) | ELISA | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340LY-S(P) | Mouse Anti-MUC5AC Recombinant Antibody (clone 58-1066); scfv Fragment | ELISA | Mouse scfv |
| HPAB-AP150-YC-S(P) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1); scFv Fragment | ELISA, Cyt | Human scFv |
| HPAB-AP151-YC-S(P) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10); scFv Fragment | ELISA, Cyt | Human scFv |
| HPAB-0566-YJ-S(P) | Mouse Anti-MUC5AC Recombinant Antibody; scFv Fragment (HPAB-0566-YJ-S(P)) | WB, ELISA, Inhib, IP, IHC, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0340LY-F(E) | Mouse Anti-MUC5AC Recombinant Antibody (clone 58-1066); Fab Fragment | ELISA | Mouse Fab |
| HPAB-AP150-YC-F(E) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1); Fab Fragment | ELISA, Cyt | Human Fab |
| HPAB-AP151-YC-F(E) | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10); Fab Fragment | ELISA, Cyt | Human Fab |
| HPAB-0566-YJ-F(E) | Mouse Anti-MUC5AC Recombinant Antibody; Fab Fragment (HPAB-0566-YJ-F(E)) | WB, ELISA, Inhib, IP, IHC, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1061 | PE-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1062 | APC-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1063 | FITC-B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC | |
| MHC-CN1064 | B*07:02/Human MUC5AC (SPFFLLLLL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP150-YC | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 1) | ELISA, Cyt | Human IgG |
| HPAB-AP151-YC | Human Anti-MUC5AC Recombinant Antibody (clone Antibody 10) | ELISA, Cyt | Human IgG |
| HPAB-0566-YJ | Mouse Anti-MUC5AC Recombinant Antibody (HPAB-0566-YJ) | WB, IHC, ELISA | Mouse IgG1 |
| VS7-0425-WR440 | Mouse Anti-MUC5AC Recombinant Antibody (clone 7E9D8) | FC | Mouse IgG2b |
| VS7-0425-WR441 | Mouse Anti-MUC5AC Recombinant Antibody (clone 8H8G6) | IHC, FC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY330 | Mouse Anti-NHP MUC5AC Recombinant Antibody (clone 45M1) | IHC, ICC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY153 | Human Anti-MUC5AC (clone Ensituximab) scFv-Fc Chimera | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4584 | Anti-MUC5AC Immunohistochemistry Kit | IHC | |
| VS-0525-XY4585 | Anti-Mouse MUC5AC Immunohistochemistry Kit | IHC |
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