Human Anti-MUSK Recombinant Autoantibody (clone MuSK1A)

CAT#: VS-1124-YJ1 Autoantibody

MuSK1A is an autoantibody that bound to MuSK and demonstrated pathogenic capacity. It recognized an epitope located in the Ig2-like domain of MuSK. Fab MuSK1A has an affinity of 0.41 nM for MuSK. The Fab of MuSK1A inhibited AChR clustering by 98.6%.

Gene Expression
Figure 1 RNA cell line category: Group enriched (LHCN-M2, RH-30)

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG4 lambda
  • Species Reactivity
  • Human
  • Clone
  • MuSK1A
  • Applications
  • FC, ELISA, IF, Inhib
  • Related Disease
  • Myasthenia gravis (MG)

Product Property

  • Purification
  • See the COA
  • Purity
  • >95% as determined by SDS-PAGE and SEC-HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • CMS9; FADS; FADS1; muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific tyrosine-protein kinase receptor
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

Secondary Antibody

Recommended Dilution Buffer

See other products for "MUSK"

Select a product category from the dropdown menu below to view related products.

CAT Product Name Application Type
VS-0724-YC923 AbPlus™ Anti-MUSK Magnetic Beads (VS-0724-YC923) IP, Protein Purification
CAT Product Name Application Type
VS-1124-YJ2 Human Anti-MUSK Recombinant Autoantibody (clone MuSK1B) FC, ELISA, IF, Inhib Human IgG4 lambda
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