Human Anti-MUSK Recombinant Autoantibody (clone MuSK1A)
CAT#: VS-1124-YJ1 Autoantibody
MuSK1A is an autoantibody that bound to MuSK and demonstrated pathogenic capacity. It recognized an epitope located in the Ig2-like domain of MuSK. Fab MuSK1A has an affinity of 0.41 nM for MuSK. The Fab of MuSK1A inhibited AChR clustering by 98.6%.

Specifications
- Host Species
- Human
- Type
- Human IgG4 lambda
- Species Reactivity
- Human
- Clone
- MuSK1A
- Applications
- FC, ELISA, IF, Inhib
- Related Disease
- Myasthenia gravis (MG)
Product Property
- Purification
- See the COA
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "MUSK"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1123z | Mouse Anti-MUSK Recombinant Antibody (clone 10G6) | ICC, IF, IHC, ELISA | Mouse IgG1 |
MOB-0075CT | Recombinant Mouse anti-Human MUSK Monoclonal antibody (EML593) | WB | |
ZG-0296C | Mouse Anti-MUSK Recombinant Antibody (ZG-0296C) | IHC, IF, ELISA | Mouse IgG |
VS3-FY2812 | Mouse Anti-Musk Recombinant Antibody (VS3-FY2812) | WB, IHC | Mouse IgG |
VS7-0425-WR447 | Mouse Anti-MUSK Monoclonal Antibody (VS7-0425-WR447) | IHC-P, IF, ICC, ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0724-YC923 | AbPlus™ Anti-MUSK Magnetic Beads (VS-0724-YC923) | IP, Protein Purification |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-1124-YJ2 | Human Anti-MUSK Recombinant Autoantibody (clone MuSK1B) | FC, ELISA, IF, Inhib | Human IgG4 lambda |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY4593 | Anti-MUSK Immunohistochemistry Kit | IHC | |
VS-0525-XY4594 | Anti-Mouse MUSK Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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