Human Anti-ORAI1 Antibody, mRNA
CAT#: TAB-756CL-mRNA
This mRNA encodes a Human antibody against ORAI1. It contains two mRNAs that encode for the heavy and light chains of the antibody.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human skin
Immunohistochemical staining of human skin shows membranous positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_A_8_3.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_A_6_6.jpg
Normal Tissue
Figure 5 Skin
Epidermal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16583/37073_B_5_8.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (NB-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000276045-ORAI1
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Specifications
- Host Species
- Human
- Specificity
- Human ORAI1
- Species Reactivity
- Human
- Related Disease
- Immune Disorder or Disease
Product Property
- Purity
- >95%
- Storage
- Store at -20°C.
Target
- Alternative Names
- ORAI1; ORAI calcium release-activated calcium modulator 1; IMD9; TAM2; ORAT1; CRACM1; TMEM142A; calcium release-activated calcium channel protein 1; protein orai-1; transmembrane protein 142A; calcium release-activated calcium modulator 1
- Gene ID
- 84876
- UniProt ID
- A0A024RBT3
REVIEWS AND Q&AS
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Specific ORAI1 Binding
The antibody produced from this mRNA specifically binds to human ORAI1, as verified in our binding assays. This approach has opened new avenues for our research into calcium release-activated calcium channels. The storage instructions were clear, and the product integrity was maintained upon arrival.
Innovative mRNA Product
This mRNA product encoding the Anti-ORAI1 antibody is a fascinating tool for our research. It allowed us to express the antibody directly in our cell systems. The high purity of the mRNA ensured good transfection efficiency and subsequent antibody production for our immune disorder studies.
Q&As
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What does this mRNA product encode?
A: This product consists of mRNA that encodes for a Human antibody against ORAI1. It contains two specific mRNAs that encode for the heavy and light chains of the antibody, allowing for expression in your experimental system.
-
What is the target of the expressed antibody?
A: The expressed antibody specifically binds to Human ORAI1 (calcium release-activated calcium modulator 1). This protein is a key component of calcium release-activated calcium channels and is a target of interest in immune disorder research.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
Primary Immunodeficiency
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| TAB-0851CL | Rat Anti-ORAI1 Recombinant Antibody (TAB-0851CL) | FC, Inhib | Rat IgG2a, κ |
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| TAB-0852CL | Rat Anti-ORAI1 Recombinant Antibody (TAB-0852CL) | FC, Inhib | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
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| TAB-0853CL | Human Anti-ORAI1 Recombinant Antibody (TAB-0853CL) | FC, Inhib | Chimeric (rat/human) IgG |
| CAT | Product Name | Application | Type |
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| TAB-0854CL | Human Anti-ORAI1 Recombinant Antibody (TAB-0854CL) | FC, Inhib | Chimeric (rat/human) IgG |
| CAT | Product Name | Application | Type |
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| TAB-0855CL | Mouse Anti-ORAI1 Recombinant Antibody (TAB-0855CL) | FuncS, FC, WB, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0856CL | Mouse Anti-ORAI1 Recombinant Antibody (TAB-0856CL) | FuncS, FC, WB, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0857CL | Mouse Anti-ORAI1 Recombinant Antibody (TAB-0857CL) | FuncS, FC, WB, Inhib | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0853CL-S(P) | Rat Anti-ORAI1 Recombinant Antibody; scFv Fragment (TAB-0853CL-S(P)) | FC | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0854CL-S(P) | Rat Anti-ORAI1 Recombinant Antibody; scFv Fragment (TAB-0854CL-S(P)) | FC | scFv |
| CAT | Product Name | Application | Type |
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| TAB-0853CL-F(E) | Human Anti-ORAI1 Recombinant Antibody; Fab Fragment (TAB-0853CL-F(E)) | FC | Chimeric (rat/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2550 | Hi-Affi™ Recombinant Rabbit Anti-ORAI1 Monoclonal Antibody (DS2550AB) | WB | IgG |
| CAT | Product Name | Application | Type |
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| MRO-2096-CN | Rabbit Anti-ORAI1 Polyclonal Antibody (MRO-2096-CN) | WB, IF, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| HPAB-0508-FY | Mouse Anti-ORAI1 Recombinant Antibody (HPAB-0508-FY) | ELISA, Inhib, Block, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
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| HPAB-0509-FY | Mouse Anti-ORAI1 Recombinant Antibody (HPAB-0509-FY) | ELISA, Block, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0508-FY-S(P) | Mouse Anti-ORAI1 Recombinant Antibody; scFv Fragment (HPAB-0508-FY-S(P)) | ELISA, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0509-FY-S(P) | Mouse Anti-ORAI1 Recombinant Antibody; scFv Fragment (HPAB-0509-FY-S(P)) | ELISA, Inhib | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0508-FY-F(E) | Mouse Anti-ORAI1 Recombinant Antibody; Fab Fragment (HPAB-0508-FY-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0509-FY-F(E) | Mouse Anti-ORAI1 Recombinant Antibody; Fab Fragment (HPAB-0509-FY-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
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| VS13-YC861 | Rabbit Anti-ORAI1 Recombinant Antibody (VS13-YC861) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0425-YC293 | Recombinant Anti-ORAI1 Vesicular Antibody, EV Displayed (VS-0425-YC293) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
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| VS-0525-XY5097 | Anti-ORAI1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY5098 | Anti-Mouse ORAI1 Immunohistochemistry Kit | IHC |
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