AbPlus™ Anti-PCNA Magnetic Beads (VS-0724-YC76)

CAT#: VS-0724-YC76

The AbPlus Anti-PCNA Magnetic Beads (VS-0724-YC76) is an innovative affinity resin which is bound with anti-PCNA specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PCNA protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line A-431 Figure 2 Colon Figure 3 Testis Figure 4 Bone marrow Figure 5 Lymph node Figure 6 RNA cell line category: Low cell line specificity

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-PCNA specific antibody
  • Target
  • PCNA
  • Immunogen
  • Synthetic peptide corresponding to the C-terminus of the human PCNA.
  • Target Species
  • Human, Rat
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
  • Alternative Names
  • Proliferating Cell Nuclear Antigen; Cyclin; DNA Polymerase Delta Auxiliary Protein; ATLD2;
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