Human Anti-PDGFRB Antibody (1B3), CHO Stable Cell Pool

Name: Human Anti-PDGFRB Antibody (1B3), CHO Stable Cell Pool
SKU: VS-1025-QX205
Rating: 5 (1 reviews)

CAT#: VS-1025-QX205

This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant 1B3. 1B3 is a Human monoclonal antibody that targets PDGFRB. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of 1B3 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line ASC TERT1

Immunofluorescent staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28499/1774_C4_13_cr5950fa3646972_selected.jpg

Normal Tissue Figure 2 Testis

Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_4_6.jpg

Normal Tissue Figure 3 Placenta

Decidual cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_2_7.jpg

Normal Tissue Figure 4 Cerebral cortex

Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_B_9_5.jpg

Normal Tissue Figure 5 Liver

Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_9_4.jpg

Normal Tissue Figure 6 Kidney

Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_8_5.jpg

RNA Expression Figure 7 RNA cell line category: Group enriched (ASC diff, ASC TERT1)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113721-PDGFRB

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Specifications

Host Cell
CHO

Product Type
Stable Cell Pool

Cell Viability
>90%

Mycoplasma Detection
Negative

Bacteria Detection
Negative

Growth Properties
Suspension

Culture Medium
VersaCHO™ Medium (VS-1025-QX582)

Complete Growth Medium
VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)

Freeze Medium
90% VersaCHO™ Medium, 10% DMSO

Growth Conditions
37°C, 5% CO₂

Size
Each vial contains at least 1×10^6 cells in 1 mL

Shipping
Dry ice

Storage
Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.

Antibody Overview

Host Species
Human

Antibody Type
Human IgG1, κ

Clone
1B3

Target
PDGFRB

Species Reactivity
Mouse

Target

Alternative Names
Pdgfrb; platelet derived growth factor receptor, beta polypeptide; Pdgfr; CD140b; PDGFR-1; AI528809

Gene ID
18596

UniProt ID
P05622

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Datasheet

Datasheet - VS-1025-QX205.pdf

MSDS

MSDS - VS-1025-QX205.pdf

COA

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