Mouse Anti-PLAU Recombinant Antibody (clone 6B6A3) (CAT#: VS7-0425-WR625)
This product is a mouse IgG1 antibody that binds to human PLAU. The antibody 6B6A3 recognizes specific amino acid domain of human PLAU (AA: 107-379). It can be used for WB, ICC, and FC assays.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line RPTEC TERT1
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/1789_A4_1_cr5bacc2acbd568_selected.jpg
(Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/1789_A4_1_cr5bacc2acbd568_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_2_7_selected.jpg
(Immunohistochemical staining of human placenta shows strong cytoplasmic and membranous positivity in trophoblastic cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_2_7_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/1886_D2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/1886_D2_1_blue_red_green.jpg
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/1819_G1_4_cr5bacc1ca11170_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/1819_G1_4_cr5bacc1ca11170_blue_red_green.jpg
Figure 5 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_B_9_5.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_B_9_5.jpg
Figure 6 Colon
(Endocrine cells
Staining:Medium
Intensity: Moderate
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Fibroblasts
Staining:High
Intensity: Strong
Goblet cells
Staining:Low
Intensity: Moderate
Quantity: <25%
Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity:>75%
Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_8_3.jpg
(Endocrine cells
Staining:Medium
Intensity: Moderate
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Fibroblasts
Staining:High
Intensity: Strong
Goblet cells
Staining:Low
Intensity: Moderate
Quantity: <25%
Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity:>75%
Peripheral nerve/ganglion
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_8_3.jpg
Figure 7 Kidney
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity:>75%
Collecting ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining:Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_9_5.jpg
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity:>75%
Collecting ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Proximal tubules (microvilli)
Staining:Medium
Intensity: Moderate)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_9_5.jpg
Figure 8 Testis
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_5_6.jpg
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_5_6.jpg
Figure 9 Prostate
(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_2_5.jpg
(Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70796/168931_A_2_5.jpg
Figure 10 RNA cell line category: Cell line enhanced (CAPAN-2, LHCN-M2, RPTEC TERT1, U-251 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000122861-PLAU
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000122861-PLAU
Specifications
- Immunogen
- Recombinant human PLAU (AA: 107-379) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human PLAU
- Species Reactivity
- Human
- Clone
- 6B6A3
- Molecule Class
- Serine Protease
- Applications
- WB, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Quebec platelet disorder (QPD)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- PLAU; plasminogen activator, urokinase; ATF; QPD; UPA; URK; u-PA; BDPLT5; urokinase-type plasminogen activator; U-plasminogen activator; plasminogen activator, urinary
- Gene ID
- 5328
- UniProt ID
- P00749
- Long Name
- Plasminogen Activator, Urokinase
- Cellular Localization
- Secreted
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Phosphoprotein; Zymogen
- Protein Refseq
- NP_001138503.2
- Function
- Hydrolase; Protease; Serine protease
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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|---|---|---|---|
| NAB-1922-sdAb | Recombinant Anti-Human Plau VHH Single Domain Antibody | IHC, IP, FC, Neut, FUNC | Llama VHH |
| NABL-024 | Recombinant Anti-human PLAU VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
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| PABC-549 | Recombinant Llama Anti-PLAU Single Domain Antibody (PABC-549) | ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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