Rabbit Anti-Plcb1 Recombinant Antibody (clone R03-6E6) (CAT#: VS3-FY1831)

• Immunogen
• Recombinant mouse phospholipase C beta 1 protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Mouse and Rat Plcb1

• Species Reactivity
• Mouse, Rat

• Clone
• R03-6E6

• Applications
• Western Blot

• MW
• The calculated weight of the target protein is approximately 138 kDa, while the observed molecular weight stands at 138 kDa.

• Related Disease
• Developmental And Epileptic Encephalopathy 12 and Malignant Migrating Focal Seizures Of Infancy

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000

• Alternative Names
• Plcb; mKIAA0581; 3110043I21Rik

• Gene ID
• 18795

• UniProt ID
• Q9Z1B3

• Cellular Localization
• Cytoplasm, Membrane, Nucleus

• Post Translation Modifications
• activity of PLCB1 and the function of the endothelial barrier (Probable). Palmitoylation by ZDHHC21 is stimulated by inflammation (PubMed:27653213).

• Protein Refseq
• NP_001139302.1

• Function
• Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors.
  Regulates the function of the endothelial barrier.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

Select a product category from the dropdown menu below to view related products.