Rabbit Anti-Plcb1 Recombinant Antibody (VS13-YC908) (CAT#: VS13-YC908)
The Rabbit Anti-Plcb1 Recombinant Antibody is specific for mouse and rat Plcb1. PLCB1 enables lamin and phospholipase C activity, involved in signaling pathways, expressed across multiple tissues, linked to disorders like encephalopathy. The anti-Plcb1 antibody can be used for Western blot (1/500-1/1000).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5334/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5334/if_selected.jpg
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining shows high expression in cerebral cortex)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5334/148012_B_8_5_val_selected.jpg
(Immunohistochemical staining shows high expression in cerebral cortex)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5334/148012_B_8_5_val_selected.jpg
Figure 3 Cerebral cortex
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4275/148706_B_8_5.jpg
(Neuronal cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4275/148706_B_8_5.jpg
Figure 4 Hippocampus
(Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4275/148706_B_8_6.jpg
(Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4275/148706_B_8_6.jpg
Figure 5 Kidney
(Collecting ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Distal tubules
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4275/148706_A_8_5.jpg
(Collecting ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Distal tubules
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4275/148706_A_8_5.jpg
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182621-PLCB1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182621-PLCB1/subcellular
Specifications
- Immunogen
- Recombinant mouse Phospholipase C beta 1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse and Rat Plcb1
- Species Reactivity
- Mouse, Rat
- Applications
- WB
- Conjugate
- NONE
- Related Disease
- Developmental and epileptic encephalopathy and myelodysplastic syndrome
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Target
- Alternative Names
- Plcb; mKIAA0581; 3110043I21Rik
- Gene ID
- 18795
- UniProt ID
- Q9Z1B3
- Long Name
- phospholipase C, beta 1
- Cellular Localization
- Cytoplasm; Membrane; Nucleus
- Protein Refseq
- NP_001139302.1
- Function
- Catalyzes the hydrolysis of 1-phosphatidylinositol 4, 5-bisphosphate into diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors.
Regulates the function of the endothelial barrier.
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
cAMP Signaling Pathway
Morphine Addiction
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PLCB1"
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2344CT | Recombinant Mouse anti-Human PLCB1 Monoclonal antibody (FQS4039) | IHC-P | |
| VS3-FY1831 | Rabbit Anti-Plcb1 Recombinant Antibody (clone R03-6E6) | WB | Rabbit IgG |
| VS3-FY2183 | Rabbit Anti-PLCB1 Recombinant Antibody (clone R39-2S-8) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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