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    Human Anti-PMEL Recombinant Antibody (VS-0723-WK139) (CAT#: VS-0723-WK139)

    This product is a chimeric (rabbit/human) IgG1 antibody that recognizes human PMEL, which is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This antibody is recommended for flow cytometry at a dilution of 1:100.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line SK-MEL-30
    Figure 1 IF staining of human cell line SK-MEL-30
    (Immunofluorescent staining of human cell line SK-MEL-30 shows localization to endoplasmic reticulum & the Golgi apparatus.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/1898_C6_19_cr5ba8a6f6e250d_selected.jpg
    Normal Tissue
    Figure 2 Kidney
    Figure 2 Kidney
    (Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_A_7_5.jpg
    Figure 3 Testis
    Figure 3 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_A_4_6.jpg
    Figure 4 Skin
    Figure 4 Skin
    (Melanocytes
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31649/144626_B_7_1.jpg
    RNA Expression
    Figure 5 RNA cell line category: Cell line enriched (SK-MEL-30)
    Figure 5 RNA cell line category: Cell line enriched (SK-MEL-30)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185664-PMEL

    Specifications

    • Immunogen
    • Recombinant human PMEL protein
    • Host Species
    • Human
    • Derivation
    • Chimeric (rabbit/human)
    • Type
    • Chimeric (rabbit/human) IgG1
    • Specificity
    • Human PMEL
    • Species Reactivity
    • Human
    • Applications
    • FC
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Purity
    • >95%
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • 1×PBS
    • Preservative
    • No Preservative
    • Storage
    • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Flow Cytometry: 1/100

    Target

    • Alternative Names
    • D12S53E; gp100; ME20; ME20-M; ME20M; P1; P100; PMEL17; SI; SIL; SILV
    • Long Name
    • Premelanosome protein

    Recommended Products

    Isotype Control

    Secondary Antibody

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "PMEL"

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    Immunotoxin Products Mouse Antibody Products MHC Tetramer Products for Cancer Rabbit Monoclonal Antibody Products IgG Antibody Products ScFv Antibody Products Fab Antibody Products MHC Tetramer Products for Virology Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    AGTO-G051E Anti-PMEL immunotoxin (Fab)-PE Cytotoxicity assay, Function study

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