Mouse Anti-PROM1 Recombinant Antibody (clone 2F8C5)
CAT#: VS7-0425-WR693
This product is a mouse IgG1 antibody that binds to human PROM1. The antibody 2F8C5 recognizes specific amino acid domain of human PROM1 (AA: 20-108). It can be used for FC assay.
Gene Expression
Normal Tissue
Figure 1 Colon
Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_7_4.jpg
Normal Tissue
Figure 3 Pancreas
Exocrine glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_2_3.jpg
Normal Tissue
Figure 4 Kidney
Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AF22, CACO-2, CAPAN-2, EFO-21, NTERA-2, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007062-PROM1
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Specifications
- Immunogen
- Recombinant human PROM1 (AA: 20-108) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human PROM1
- Species Reactivity
- Human
- Clone
- 2F8C5
- Molecule Class
- Pentaspan Transmembrane Glycoprotein
- Applications
- FC
- Conjugate
- Unconjugated
- Related Disease
- Retinitis pigmentosa 41 (RP41); Cone-rod dystrophy 12 (CORD12); Stargardt disease 4 (STGD4); Macular dystrophy, retinal, 2 (MCDR2)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- PROM1; MSTP061; HProminin; Prominin 1; Prominin-Like Protein 1; Macular Dystrophy, Retinal 2; STGD4; AC133; MCDR2; Prominin (Mouse)-Like 1; PROML1; CD133; Prominin-1; Hematopoietic Stem Cell Antigen; RP41; Stargardt Disease 4 (Autosomal Dominant); Antigen
- Gene ID
- 8842
- UniProt ID
- O43490
- Long Name
- Prominin 1
- Cellular Localization
- Cell membrane; Cell projection; Cilium; Endoplasmic reticulum; Membrane
- Post Translation Modifications
- Acetylation; Glycoprotein; Phosphoprotein
- Protein Refseq
- NP_001139319.1
- Function
- May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617).; Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439)
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "PROM1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1990z | Mouse Anti-PROM1 Recombinant Antibody (clone 41D7) | WB, FC, IHC | Mouse IgG1 |
| HPAB-0088-FY | Human Anti-PROM1 Recombinant Antibody (HPAB-0088-FY) | FC | Human IgG1 |
| MRO-1733-CN | Rabbit Anti-PROM1 Polyclonal Antibody (MRO-1733-CN) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-1396-FY | Human Anti-PROM1 Recombinant Antibody (clone H133) | FC | Humanized IgG |
| VS7-0425-WR694 | Mouse Anti-PROM1 Monoclonal Antibody (VS7-0425-WR694) | IHC-P, IF, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B028(A) | Recombinant Anti-human PROM1 Intrabody [(D-Arg)9] | ELISA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B028(G) | Recombinant Anti-human PROM1 Intrabody [+36 GFP] | PCA, WB, FuncS | scFv-(+36GFP) |
| IAB-B028(T) | Recombinant Anti-human PROM1 Intrabody [Tat] | FACS, ELISA, IF, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G057S | Anti-PROM1 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0375CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (293AC1C3H9) | FC | Chimeric (mouse/human) |
| TAB-0376CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (SDIE 293) | FC | Chimeric (mouse/human) |
| TAB-0377CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (W6B3H10) | FC | Chimeric (mouse/human) |
| TAB-0378CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment (SDIE W6B3) | FC | Chimeric (mouse/human) |
| TAB-0379CL-F(E) | Anti-Mouse PROM1 Recombinant Antibody Fab Fragment | FC | Chimeric (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-S(P) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0088-FY-S(P) | Human Anti-PROM1 Recombinant Antibody; scFv Fragment (HPAB-0088-FY-S(P)) | FC | Human scFv |
| HPAB-1396-FY-F(E) | Human Anti-PROM1 Recombinant Antibody (clone H133); scFv Fragment | FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-F(E) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0088-FY-F(E) | Human Anti-PROM1 Recombinant Antibody; Fab Fragment (HPAB-0088-FY-F(E)) | FC | Human Fab |
| HPAB-1396-FY-S(P) | Human Anti-PROM1 Recombinant Antibody (clone H133); Fab Fragment | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-019CN | Mouse Anti-PROM1 Recombinant Antibody (NS-019CN) | ELISA, IF, IHC, FC | Mouse IgG |
| NS-019CN-F(E) | Mouse Anti-PROM1 Recombinant Antibody; Fab Fragment (NS-019CN-F(E)) | ELISA, IF, IHC, FC | Mouse Fab |
| NS-019CN-S(P) | Mouse Anti-PROM1 Recombinant Antibody; scFv Fragment (NS-019CN-S(P)) | ELISA, IF, IHC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1161 | PE-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1162 | APC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1163 | FITC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1164 | A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-YF689 | A*02:01/Human Prominin1 (YLQWIEFSI) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0060-FY | Rabbit Anti-PROM1 Recombinant Antibody (clone AFY0031) | IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC86 | Mouse Anti-PROM1 Recombinant Antibody (VS-0924-YC86) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC87 | Rabbit Anti-PROM1 Antibody (VS-0924-YC87) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY181 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (clone 293C3) | FC | Mouse IgG2b, kappa |
| VS-0225-XY182 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS-0225-XY182) | FC | Mouse IgG1, kappa |
| VS13-YC944 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS13-YC944) | WB, IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC266 | Recombinant Anti-PROM1 Vesicular Antibody, EV Displayed (VS-0425-YC266) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5735 | Anti-PROM1 Immunohistochemistry Kit | IHC |
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