Mouse Anti-SDC1 Recombinant Antibody (VS-1225-XY230)
CAT#: VS-1225-XY230
It aids SDC1 localization in tissues via IHC, while enabling quantification through ELISA and WB. This antibody is a versatile tool for multi-platform SDC1 research.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to focal adhesion sites.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_7_3.jpg
Normal Tissue
Figure 4 Testis
Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_4_6.jpg
Normal Tissue
Figure 5 Placenta
Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_1_7.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (HBEC3-KT, hTCEpi, U-251 MG, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115884-SDC1
❮
❯
Specifications
- Host Animal
- Mouse
- Applications
- WB
- Specificity
- SDC1
- Target
- SDC1
- Species Reactivity
- Human
- Type
- Mouse IgG1
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Protein A purified
- Format
- Lyophilized
- Buffer
- PBS with 8% trehalose
- Preservative
- No preservative
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- Syndecan-1 (SDC1), or CD138, is a transmembrane proteoglycan expressed on plasma cells, epithelial cells, and stromal cells. It binds growth factors, chemokines, and extracellular matrix molecules, regulating cell adhesion, signaling, and angiogenesis. CD138 is highly expressed on malignant plasma cells in multiple myeloma (MM) and is a diagnostic marker for the disease. It is targeted by monoclonal antibodies (elotuzumab) and ADCs, which induce ADCC and inhibit signaling pathways critical for MM cell survival. CD138 targeting is integral to MM treatment, particularly in combination with other agents like proteasome inhibitors.
- Alternative Names
- CD138, SDC, SYND1, syndecan
- Gene ID
- 6382
- UniProt ID
- P18827
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
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- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| TAB-495CT | Mouse Anti-SDC1 Recombinant Antibody (TAB-495CT) | FC, WB | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| HPAB-0324-CN | Human Anti-SDC1 Recombinant Antibody (HPAB-0324-CN) | ELISA, FC | Humanized IgG3, κ |
| CAT | Product Name | Application | Type |
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| HPAB-0326-CN | Human Anti-SDC1 Recombinant Antibody (HPAB-0326-CN) | ELISA, FC | Humanized IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0324-CN-S(P) | Human Anti-SDC1 Recombinant Antibody; scFv Fragment (HPAB-0324-CN-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0326-CN-S(P) | Human Anti-SDC1 Recombinant Antibody; scFv Fragment (HPAB-0326-CN-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0324-CN-F(E) | Human Anti-SDC1 Recombinant Antibody; Fab Fragment (HPAB-0324-CN-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0326-CN-F(E) | Human Anti-SDC1 Recombinant Antibody; Fab Fragment (HPAB-0326-CN-F(E)) | ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-086CN | Human Anti-SDC1 Recombinant Antibody (NS-086CN) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-087CN | Human Anti-SDC1 Recombinant Antibody (NS-087CN) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-086CN-F(E) | Human Anti-SDC1 Recombinant Antibody; Fab Fragment (NS-086CN-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-087CN-F(E) | Human Anti-SDC1 Recombinant Antibody; Fab Fragment (NS-087CN-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-086CN-S(P) | Human Anti-SDC1 Recombinant Antibody; scFv Fragment (NS-086CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-089CN | Mouse Anti-SDC1 Recombinant Antibody (NS-089CN) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2546LY-F(E) | Human Anti-SDC1 Recombinant Antibody; Fab Fragment (HPAB-2546LY-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2546LY-S(P) | Human Anti-SDC1 Recombinant Antibody; scFv Fragment (HPAB-2546LY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX1001 | Mouse Anti-SDC1 Recombinant Antibody (clone 587CT7.3.6.5) | WB, ICC, FC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY193 | CytoStream™ Mouse Anti-SDC1 Recombinant Antibody (VS-0225-XY193) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY16 | Human Anti-SDC1 scFv-Fc Chimera (VS-0325-FY16) | ELISA, FC, Cyt | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY153 | Human Anti-SDC1 scFv-Fc Chimera (VS-0325-FY153) | ADCC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC134 | Recombinant Anti-SDC1 Vesicular Antibody, EV Displayed (VS-0425-YC134) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6401 | Anti-SDC1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6402 | Anti-Mouse SDC1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6404 | Anti-Rat SDC1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC300 | SmartAb™ Recombinant Anti-SDC1 pH-dependent Antibody (VS-0825-YC300) | ELISA, FC | Human IgG3 kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY221 | Mouse Anti-SDC1 Recombinant Antibody (VS-1225-XY221) | IHC, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY222 | Mouse Anti-SDC1 Recombinant Antibody (VS-1225-XY222) | IHC, ICC, IF, ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY223 | Mouse Anti-SDC1 Recombinant Antibody (VS-1225-XY223) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY224 | Mouse Anti-SDC1 Recombinant Antibody (VS-1225-XY224) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY225 | Mouse Anti-SDC1 Recombinant Antibody (VS-1225-XY225) | WB, IHC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY923 | Rabbit Anti-SDC1 Recombinant Antibody (VS-1125-XY923) | WB, IHC, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY924 | Rabbit Anti-SDC1 Recombinant Antibody (VS-1125-XY924) | WB, IHC, ICC, IF, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY925 | Rabbit Anti-SDC1 Recombinant Antibody (VS-1125-XY925) | WB, IHC, ICC, IF, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1125-XY926 | Rabbit Anti-SDC1 Recombinant Antibody (VS-1125-XY926) | WB, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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