CytoStream™ Rabbit Anti-SDC1 Recombinant Antibody (VS13-YC1044) (CAT#: VS13-YC1044)
The CytoStream™ Rabbit Anti-SDC1 Recombinant Antibody is specific for human, mouse and rat SDC1. SDC1 encodes a syndecan family proteoglycan mediating cellular interactions and implicated in tumor types via altered expression. The anti-SDC1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/1000).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/if_selected.jpg
Figure 2 Cerebral cortex
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_B_8_5.jpg
(Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_B_8_5.jpg
Figure 3 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_7_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_7_3.jpg
Figure 4 Testis
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_4_6.jpg
(Pachytene spermatocytes Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_4_6.jpg
Figure 5 Placenta
(Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_1_7.jpg
(Syncytiotrophoblasts - cell body Staining: High Intensity: Strong Quantity:>75% Syncytiotrophoblasts - microvilli Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_1_7.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_7_8.jpg
(Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6185/40538_A_7_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (HBEC3-KT, hTCEpi, U-251 MG, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115884-SDC1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115884-SDC1
Specifications
- Immunogen
- Recombinant human Syndecan 1, aa 13-274.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SDC1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Monoclonal Gammopathy of Uncertain Significance and Endometritis
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/2000
Immunofluorescence (IF-cell): 1/100
Immunofluorescence (IF-tissue): 1/50
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/1000
Target
- Alternative Names
- Syndecan 1; Syndecan Proteoglycan 1; CD138 Antigen; SYND1; SDC; Heparan Sulfate Proteoglycan Fibroblast Growth Factor Receptor; Syndecan-1; Syndecan; CD138;
- Gene ID
- 6382
- UniProt ID
- P18827
- Long Name
- Syndecan 1
- Cellular Localization
- Membrane; Secreted
- Protein Refseq
- XP_005262677.1
- Function
- Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix (By similarity).
Regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413).
Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2506z | Mouse Anti-SDC1 Recombinant Antibody (clone 22B3) | WB, ELISA, FC, ICC | Mouse IgG1 |
| MOB-0294MZ | Recombinant Mouse Anti-Human Syndecan 1 Antibody (clone NI16) | IHC | Mouse antibody |
| VS3-CJ734 | Mouse Anti-SDC1 Recombinant Antibody (VS3-CJ734) | WB | Mouse IgG1 |
| VS3-XY1398 | Mouse Anti-SDC1 Recombinant Antibody (clone 1A3H4) | ELISA, WB, IHC, FC, ICC | Mouse IgG1 |
| VS3-XY3496 | Rabbit Anti-SDC1 Recombinant Antibody (clone R07-9H1) | WB, IHC-P, ICC, IF | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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