AbPlus™ Anti-SIRT1 Magnetic Beads (CBACN-504)
CAT#: VS-0424-XY235
The AbPlus Anti-SIRT1 Magnetic Beads (CBACN-504) is an innovative affinity resin which is bound with anti-SIRT1 specific antibody (CBACN-504). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SIRT1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6295/43_F3_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52351/826_A6_1_selected.jpg
Normal Tissue
Figure 3 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6295/18379_A_4_6.jpg
Normal Tissue
Figure 4 Adrenal gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/6295/18379_B_6_5.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000096717-SIRT1
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-SIRT1 specific antibody (CBACN-504)
- Target
- SIRT1
- Immunogen
- Human SIRT1 (aa 700-800)
- Target Species
- Human
- Antibody Clone
- CBACN-504
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.
- Alternative Names
- Sirtuin 1; Regulatory Protein SIR2 Homolog 1; SIR2-Like Protein 1; SIR2L1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog) 1; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); NAD-Dependent Protein Deacetylase Sirtuin-1
- Gene ID
- 23411
- UniProt ID
- Q96EB6
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "SIRT1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3980z | Mouse Anti-SIRT1 Recombinant Antibody (clone 4G3) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MRO-2188-CN | Rabbit Anti-SIRT1 Polyclonal Antibody (MRO-2188-CN) | WB, IHC, FC | Rabbit IgG |
| ZG-0071U | Rabbit Anti-SIRT1 Recombinant Antibody (clone 9E9) | ELISA, IHC, IF | Rabbit IgG |
| VS3-WK1101 | Rabbit Anti-SIRT1 Recombinant Antibody (VS3-WK1101) | WB, ICC, IF, IHC, IP | Rabbit IgG |
| VS7-0425-WR854 | Mouse Anti-SIRT1 Monoclonal Antibody (VS7-0425-WR854) | WB, IHC-P, IF, ICC, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0777MZ | Chicken Anti-SIRT1 Polyclonal IgY | IHC, IF, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3267 | Hi-Affi™ Recombinant Rabbit Anti-SIRT1 Monoclonal Antibody (DS3267AB) | IP, WB | IgG |
| MOR-0043-FY | Rabbit Anti-SIRT1 Recombinant Antibody (clone AFY0014) | ICC, IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC526 | AbPlus™ Anti-SIRT1 Magnetic Beads (VS-0724-YC526) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY480 | Mouse Anti-NHP SIRT1 Recombinant Antibody (clone 1F3) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2070 | Anti-SIRT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6601 | Anti-Human SIRT1 Immunohistochemistry Kit | IHC |
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