Mouse Anti-SLC6A3 Recombinant Antibody (clone K2-3f); Fab Fragment (CAT#: FAMAB-0081-YC-F(E))
Provided is a monoclonal antibody, K2-3f specifically binding to the human dopamine transporter (hDAT). K2-3f showed the highest avidity to hDAT and and excellent mimicry of the cocaine molecule completely inhibited cocaine binding at a molar concentration closely resembling in vivo conditions while allowing approximately 90% of equimolar dopamine uptake.
Specific Inquiry
Subcellular Location
Normal Tissue
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13602/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13602/if_selected.jpg
Figure 2 Low expression in rectum.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78172/164529_A_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78172/164529_A_4_3_val_selected.jpg
Figure 3 Cerebral cortex
(Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78172/164529_B_8_5.jpg
(Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78172/164529_B_8_5.jpg
Specifications
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human SLC6A3
- Species Reactivity
- Human
- Clone
- K2-3f
- Applications
- ELISA, IF, WB
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2033z | Mouse Anti-SLC6A3 Recombinant Antibody (clone 33G5) | ELISA, WB, IHC | Mouse IgG1 |
| FAMAB-0081YC | Mouse Anti-SLC6A3 Recombinant Antibody (clone K2-3f) | ELISA, IF, WB | Mouse IgG |
| VS1-YJ48 | Mouse Anti-Slc6a3 Recombinant Antibody (clone 6V-23-23) | IF, WB | Mouse IgG1 |
| VS1-YJ49 | Mouse Anti-Slc6a3 Recombinant Antibody (clone 6V-23-23), HRP | WB, IHC-P | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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