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SLC6A3
Loading...Anti-SLC6A3 Products
- Mouse Anti-SLC6A3 Antibody (clone K2-3f), mRNA (FAMAB-0081YC-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Mouse, Rat. Does not react with Human
- Type: Mouse IgG1
- Application: WB, IHC-P
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- Species Reactivity: Mouse, Rat. Does not react with Human
- Type: Mouse IgG1
- Application: IF, WB
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- Mouse Anti-SLC6A3 Recombinant Antibody (clone K2-3f) (FAMAB-0081YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IF, WB
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- Mouse Anti-SLC6A3 Recombinant Antibody (clone K2-3f); scFv Fragment (FAMAB-0081-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IF, WB
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- Mouse Anti-SLC6A3 Recombinant Antibody (clone K2-3f); Fab Fragment (FAMAB-0081-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IF, WB
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- Species Reactivity: Human
- Target: SLC6A3
- Host Animal: Mouse
- Application: ELISA, FC, Cell-uptake
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- Anti-SLC6A3 Immunohistochemistry Kit (VS-0525-XY6692)
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- Species Reactivity: Human
- Target: SLC6A3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]
Protein class
Disease related genes, FDA approved drug targets, Metabolic proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Alveolar cells type 2, Smooth muscle cells, Cardiomyocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Homooligomer; disulfide-linked (Ref. 14). Interacts with PRKCABP and TGFB1I1 (PubMed:11343649, PubMed:12177201). Interacts (via N-terminus) with SYNGR3 (via N-terminus) (By similarity). Interacts with SLC18A2 (By similarity). Interacts with TOR1A (ATP-bound); TOR1A regulates SLC6A3 subcellular location (PubMed:15505207). Interacts with alpha-synuclein/SNCA (PubMed:26442590). Interacts with SEPTIN4 (By similarity).
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