Rabbit Anti-SOX10 Recombinant Antibody (VS3-CJ1054)
CAT#: VS3-CJ1054
This product is a rabbit antibody that recognizes human, mouse, and rat SOX10.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68898/1371_E3_1_selected.jpg
Normal Tissue
Figure 2 High expression in cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3171/9957_B_9_5.jpg
Normal Tissue
Figure 3 Salivary gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3171/9957_B_1_1.jpg
Normal Tissue
Figure 4 Colon
Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3171/9957_A_8_3.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (SK-MEL-30, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100146-SOX10
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Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat SOX10
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry.
Target
- Alternative Names
- DOM; WS4; PCWH; WS2E; WS4C; SOX-10
- Gene ID
- 6663
- UniProt ID
- P56693
- Cellular Localization
- Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane, Nucleus
- Protein Refseq
- NP_008872.1
- Function
- Transcription factor that plays a central role in developing and mature glia (By similarity).
Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity).
Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity).
Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087).
Transcriptional activator of MBP, via binding to the gene promoter (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SOX10"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3374 | Hi-Affi™ Recombinant Rabbit Anti-SOX10 Monoclonal Antibody (DS3374AB) | WB, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-083CN | Mouse Anti-SOX10 Recombinant Antibody (NS-083CN) | WB, ELISA, ICC, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-083CN-F(E) | Mouse Anti-SOX10 Recombinant Antibody; Fab Fragment (NS-083CN-F(E)) | WB, ELISA, ICC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-083CN-S(P) | Mouse Anti-SOX10 Recombinant Antibody; scFv Fragment (NS-083CN-S(P)) | WB, ELISA, ICC, IHC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1422-CN | Recombinant Mouse Anti-SOX10 Monoclonal Antibody (1-11) | WB, IHC | Mouse IgG1 |
| MRO-1423-CN | Recombinant Rabbit Anti-SOX10 Monoclonal Antibody (CBACN-520) | WB, IF | Rabbit IgG |
| MRO-1424-CN | Recombinant Rabbit Anti-SOX10 Monoclonal Antibody (CBACN-521) | WB, IF, IHC | Rabbit IgG |
| VS3-XY1454 | Mouse Anti-SOX10 Recombinant Antibody (clone 2E7B5) | ELISA, WB, FC | Mouse IgG1 |
| VS3-XY1455 | Mouse Anti-SOX10 Recombinant Antibody (clone 2E7E8) | ELISA, WB, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2148 | Anti-SOX10 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6815 | Anti-Mouse SOX10 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6814 | Anti-Human SOX10 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6816 | Anti-Rat SOX10 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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