Mouse Anti-TIGIT Recombinant Antibody (clone 4A5)

CAT#: VS11-QX135

This product is a recombinant mouse antibody that recognizes TIGIT. This antibody can block the binding of TIGIT to its ligand CD155. This antibody can be used for the following applications: ELISA, FC, Block.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (HDLM-2)

Specifications

  • Immunogen
  • Recombinant human TIGIT extracellular region Fc fusion protein
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Human TIGIT
  • Species Reactivity
  • Human
  • Clone
  • 4A5
  • Applications
  • ELISA, FC, Block
  • Conjugate
  • Unconjugated

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • 1 mg/mL (Please refer to the vial label for the specific concentration.)
  • Buffer
  • 0.2 μm filtered solution in PBS
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipped at 4°C.

Target

  • Alternative Names
  • T Cell Immunoreceptor With Ig And ITIM Domains; V-Set And Immunoglobulin Domain-Containing Protein 9; V-Set And Transmembrane Domain-Containing Protein 3; T-Cell Immunoreceptor With Ig And ITIM Domains; VSIG9, VSTM3; VSIG9
  • Long Name
  • T-cell immunoreceptor with Ig and ITIM domains
  • Function
  • Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Isotype Control

Recommended Dilution Buffer

Secondary Antibody

See other products for "TIGIT"

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CAT Product Name Application Type
HPAB-0019CQ Mouse Anti-TIGIT Recombinant Antibody (HPAB-0019CQ) ELISA, FC, Inhib Mouse IgG2a, κ
HPAB-0020CQ Mouse Anti-TIGIT Recombinant Antibody (HPAB-0020CQ) ELISA, FC, Inhib Mouse IgG2a, κ
HPAB-0021CQ Mouse Anti-TIGIT Recombinant Antibody (HPAB-0021CQ) ELISA, FC, FuncS Mouse IgG2a, κ
HPAB-0022CQ Human Anti-TIGIT Recombinant Antibody (HPAB-0022CQ) ELISA, FC, Block, FuncS Humanized IgG1, κ
HPAB-0023CQ Human Anti-TIGIT Recombinant Antibody (HPAB-0023CQ) ELISA, FC, Block, FuncS Humanized IgG1, κ
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VS-0724-XY41 Hamster Anti-Tigit Agonistic Antibody (clone 4D4) FC, Agonistic assays Hamster IgG, kappa
VS-0724-XY42 Rabbit Anti-Tigit Agonistic Antibody (VS-0724-XY42) FC, Agonistic assays Rabbit IgG, kappa
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VS-0325-FY8 Human Anti-TIGIT scFv-Fc Chimera (VS-0325-FY8) ELISA Human IgG1, scFv-Fc
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VS-0425-YC105 Recombinant Anti-TIGIT Vesicular Antibody, EV Displayed (VS-0425-YC105) ELISA, FC, Inhib, Cell-uptake
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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