The monoclonal antibody 1418-1 is specific for the capsid of human parvovirus B19, which can be used to detect human parvovirus. Human mAb 1418-1 reacts specifically with the structural protein VP1 unique region of parvovirus B19.
Figure 1 Accessibility of VP1u in native B19 capsids.
Immunoprecipitation of B19 capsids from three different B19-containing human serum samples by MAb 1418-1 (VP1u) and MAb 860-55D (Caps). While MAb 860-55D recognized and efficiently immunoprecipitated the capsids present in the serum, no reactivity was observed with MAb 1418-1.
Ros, C., Gerber, M., & Kempf, C. (2006). Conformational changes in the VP1-unique region of native human parvovirus B19 lead to exposure of internal sequences that play a role in virus neutralization and infectivity. Journal of virology, 80(24), 12017-12024.
Figure 2 Stability of the internal conformation of VP1u in native capsids.
B19 capsids were subjected to freeze-thaw cycles (2 and 10) or to a long period of storage (10 weeks) at 4°C. Capsids were immunoprecipitated with MAb 1418-1 (V; against VP1u) or 860-55D (C; against intact capsids).
Ros, C., Gerber, M., & Kempf, C. (2006). Conformational changes in the VP1-unique region of native human parvovirus B19 lead to exposure of internal sequences that play a role in virus neutralization and infectivity. Journal of virology, 80(24), 12017-12024.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-088 | Recombinant Human Anti-EV71 VP1 Antibody (D5) | Neut, FuncS | IgG |
PABW-074 | Recombinant Mouse Anti-HRV14 VP1 Antibody (17-IA) | Neut | IgG |
PABC-075 | Recombinant Mouse Anti-HRV14 VP1 Antibody (1-IA) | Neut | IgG |
PABL-390 | Recombinant Mouse Anti-AAV VP1 Antibody (A20) | ICC, IF | IgG |
HPAB-J0275-YC | Recombinant Mouse Anti-VP1 Antibody (20D12) | ELISA, FuncS | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-088 | Recombinant Human Anti-EV71 VP1 Antibody scFv Fragment (D5) | Neut, FuncS | scFv |
PFBW-136 | Recombinant Mouse Anti-AAV VP1 Antibody Fab Fragment (A20) | WB | Fab |
PSBL-390 | Recombinant Mouse Anti-AAV VP1 Antibody scFv Fragment (A20) | WB, ELISA, FuncS, IP, DB, Neut | scFv |
FAMAB-0138-CN-S(P) | Recombinant Human Anti-VP1 Antibody scFv Fragment (1418-1) | WB, ELISA, FC | Human scFv |
HPAB-AP484-YC-S(P) | Human Anti-VP1 Recombinant Antibody; scFv Fragment (HPAB-AP484-YC-S(P)) | ELISA, FC, IF, IHC, Dot, WB, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-088 | Recombinant Human Anti-EV71 VP1 Antibody Fab Fragment (D5) | Neut, FuncS | Fab |
PFBL-089 | Recombinant Mouse Anti-EV71 VP1 Antibody Fab Fragment (E19) | Neut, ELISA, FuncS | Fab |
PFBW-074 | Recombinant Mouse Anti-HRV14 VP1 Antibody Fab Fragment (17-IA) | Neut | IgG |
PFBC-075 | Recombinant Mouse Anti-HRV14 VP1 Antibody Fab Fragment (1-IA) | Neut | IgG |
HPAB-J0275-YC-F(E) | Recombinant Mouse Anti-VP1 Antibody Fab Fragment (20D12) | ELISA, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN1333 | PE-A*01:01/Virus VP1 (SADNNNSEY) MHC Tetramer | FCM, IHC | |
MHC-CN1334 | APC-A*01:01/Virus VP1 (SADNNNSEY) MHC Tetramer | FCM, IHC | |
MHC-CN1335 | FITC-A*01:01/Virus VP1 (SADNNNSEY) MHC Tetramer | FCM, IHC | |
MHC-CN1336 | A*01:01/Virus VP1 (SADNNNSEY) MHC Tetramer | FCM, IHC | |
MHC-CN1337 | PE-A*02:01/Virus VP1 (ILMWEAVTL) MHC Tetramer | FCM, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0504-YJ-VHH | Llama Anti-VP1 Recombinant Antibody (HPAB-0504-YJ-VHH) | ELISA, IF, Inhib, WB | Llama VHH |
HPAB-0505-YJ-VHH | Llama Anti-VP1 Recombinant Antibody (HPAB-0505-YJ-VHH) | ELISA, IF, Inhib, WB | Llama VHH |
HPAB-0506-YJ-VHH | Llama Anti-VP1 Recombinant Antibody (HPAB-0506-YJ-VHH) | ELISA, IF, Inhib, WB | Llama VHH |
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