Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S13)
CAT#: VS-0323-CJ70
This chicken anti-ZIKV E antibody (clone ZIKVEF3S13) is a product that recognizes Zika virus envelope (ZIKV_E) protein.
Specifications
- Immunogen
- ZIKV_E recombinant proteins with His-tag
- Host Species
- Chicken
- Type
- Chicken IgY
- Specificity
- Zika virus envelope (ZIKV_E) protein
- Species Reactivity
- ZIKV
- Clone
- ZIKVEF3S13
- Applications
- ELISA, WB
- Conjugate
- Unconjugated
- Related Disease
- Meningoencephalitis; Myelitis; Guillain-Barré syndrome; Microcephaly
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in ELISA, Western Blot.
Target
- Alternative Names
- ZIKV_gp1
- Gene ID
- 7751225
- UniProt ID
- EZIKV
- Sequence Similarities
- In the N-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0-1 NS5-type methyltransferase family.
- Cellular Localization
- Virion; Host nucleus; Host cytoplasm
- Post Translation Modifications
- Envelope protein E:
N-glycosylation plays a role in virulence in mammalian and mosquito hosts, but may have no effect on neurovirulence.
Ubiquitination by host TRIM7 promotes virus attachment and fusion of the virus and the host endosome membrane.
- Protein Refseq
- YP_002790881.1
- Function
- Envelope protein E:
Binds to host cell surface receptors and mediates fusion between viral and cellular membranes. Efficient virus attachment to cell is, at least in part, mediated by host HAVCR1 in a cell-type specific manner (By similarity).
In addition, host NCAM1 can also be used as entry receptor (By similarity).
Interaction with host HSPA5 plays an important role in the early stages of infection as well (By similarity).
Envelope protein is synthesized in the endoplasmic reticulum and forms a heterodimer with protein prM. The heterodimer plays a role in virion budding in the ER, and the newly formed immature particle is covered with 60 spikes composed of heterodimers between precursor prM and envelope protein E. The virion is transported to the Golgi apparatus where the low pH causes the dissociation of PrM-E heterodimers and formation of E homodimers. PrM-E cleavage is inefficient, many virions are only partially matured and immature prM-E proteins could play a role in immune evasion (By similarity).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
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Secondary Antibody
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Recommended Dilution Buffer
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See other products for "ZIKV E"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-264 | Recombinant Human Anti-ZIKV E Antibody (C10) | ELISA, Neut, FuncS | Human IgG |
| FAMAB-1560CQ | Human Anti-ZIKV E Recombinant Antibody (clone A9E) | Neut, WB, ELISA | Human IgG1 |
| FAMAB-1790CQ | Human Anti-ZIKV E Recombinant Antibody (clone ZKA185) | Neut | Human IgG1 |
| VS-0323-CJ67 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF2L01) | ELISA, WB | Chicken IgY |
| VS-0323-CJ68 | Chicken Anti-ZIKV E Recombinant Antibody (clone ZIKVEF3S06) | ELISA, WB | Chicken IgY |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-264 | Recombinant Human Anti-ZIKV E Antibody Fab Fragment (C10) | ELISA, Neut | Human Fab |
| CAT | Product Name | Application | Type |
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| PSBC-264 | Recombinant Human Anti-ZIKV E Antibody scFv Fragment (C10) | ELISA, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC195 | Recombinant Anti-ZIKV E (Domain II x Domain III) Biparatopic Antibody, Tandem scFv (Clone SMZAb2 x Clone SMZAb1) | ELISA, Neut | Tandem scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-XY195 | Human Anti-ZIKV E Vaccinal Antibody (VS-0625-XY195) | ELISA, FC, Neut | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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