Anti-DLL3 (clone SC16.13)-PBD dimers ADC (CAT#: ADC-139CL)

• Antibody Overview
• Anti-DLL3 Antibody Humanized SC16.13

• Clone
• SC16.13

• Drug
• pyrrolobenzodiazepine (PBD) dimers

• Drug Class/Description
• Class: Pyrrolobenzodiazepine (PBD) dimmers
  Description: Pyrrolobenzodiazepine (PBD) dimmers are highly cytotoxic DNA cross-linking agents. PBDs exert their biological activity through covalent binding via their N10-C11imine/carbinolamine moieties to the C2-amino position of a guanine residue within the minor groove of DNA.

• Introduction
• This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Alternative Names
• DLL3; delta-like 3 (Drosophila); SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3;

• Gene ID
• 10683

• UniProt ID
• Q9NYJ7

• ADC-134CL
• Anti-DLL3 (clone SC16.13)-PBD dimers ADC

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