Human Anti-HIV-1 gp41 (clone A2) scFv-Fc Chimera (CAT#: VS-0325-FY129)
The Anti-HIV-1 gp41 scFv-Fc Antibody is a unique fusion protein designed for potential research and diagnostic applications related to HIV-1 infection. This antibody combines a single-chain variable fragment (scFv) specific for a conformational epitope in the gp41 subunit of the HIV-1 envelope glycoprotein with an IgG1 Fc domain. The scFv component selectively binds to the trimeric form of gp41, a conformation associated with the functional viral spike.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Specifications
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- HIV-1 gp41
- Species Reactivity
- Human immunodeficiency virus 1 (HIV-1)
- Clone
- A2
- Applications
- Neutralization, ADCC
- Related Disease
- HIV-1 infection
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- HIV-1 gp41 Env; Human immunodeficiency virus 1 Envelope glycoprotein; HIV-1 gp41; Human immunodeficiency virus 1; Envelope glycoprotein; Env
- UniProt ID
- Q0GHH5
- Long Name
- Human Immunodeficiency Virus 1 Envelope Glycoprotein
- Function
- HIV-1 gp41 is a transmembrane glycoprotein of the HIV-1 envelope, essential for viral fusion with host cells. It mediates the entry of the virus and is a target for antiviral drugs.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-486 | Recombinant Anti-HIV-1 gp41 Antibody | WB, Dot, FuncS | IgG |
| PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
| PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
| PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
| PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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