Recombinant Human Anti-IL-17R Soluble TCR (IF8) (C-Cys) (CAT#: VS-0622-YF3978)
Human TCR (IF8) recognizes IL-17R peptide (FITGISILL) in the context of HLA-DRB5. Soluble TCR is expressed with C-terminal Cys strategy (TRAV-TRAC partial-Cys, TRBV-TRBC partial-Cys). Depending the C-terminal Cys, two chains form heterodimer. Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
Figure 3 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
Figure 4 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
Specifications
- Host Species
- Human
- Target
- IL-17R
- Species Reactivity
- Human
- Epitope
- FITGISILL
- MHC
- HLA-DRB5
- Clone
- IF8
- Type
- Soluble TCR (C-Cys)
- Related Disease
- Breast cancer
- TCR Expression Strategy
- C-Cys strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on C-terminal Cys. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- CANDF5, CD217, CDw217, IL-17RA, IL17R, IMD51, hIL-17R
- Gene ID
- 23765
- UniProt ID
- Q96F46
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2670z | Mouse Anti-IL17RA Recombinant Antibody (clone 42A2) | WB, FC, Neut | Mouse IgG1 |
| MOB-019LC | Rat Anti-Il17ra Recombinant Antibody (clone YC125) | FC, FuncS | Rat IgG |
| HPAB-0318-WJ | Human Anti-IL17RA Recombinant Antibody (HPAB-0318-WJ) | ELISA, Neut | Humanized IgG |
| HPAB-1557-FY | Human Anti-IL17RA Recombinant Antibody (HPAB-1557-FY) | FC, Inhib | Human IgG |
| VS-0723-WK267 | Rabbit Anti-IL17RA Recombinant Antibody (VS-0723-WK267) | ELISA, FC | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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