Recombinant Human Anti-IL17RA Soluble TCR (IF8) (KIH) (CAT#: VS-0622-YF7262)
Human TCR (IF8) recognizes IL17RA peptide (FIMGISILL) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
Figure 2 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
Figure 3 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
Figure 4 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
Specifications
- Host Species
- Human
- Target
- IL17RA
- Epitope
- FIMGISILL
- MHC
- HLA-A2
- Clone
- IF8
- Type
- Soluble TCR (KIH)
- Related Disease
- Rheumatoid arthritis
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- Interleukin 17 Receptor A variant FIT_TM; FIMGISILL
Downloads
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-093 | Recombinant Anti-human IL17RA VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-134 | Human Anti-IL17RA Recombinant Antibody (TAB-134) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Human IgG2, κ |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-217 | Anti-Human IL17RA Recombinant Antibody (Ixekizumab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG4 - kappa |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1230CQ | Mouse Anti-IL17RA Recombinant Antibody (VMC192) | FuncS, Neut | Mouse IgG1, κ |
| NEUT-1231CQ | Mouse Anti-IL17RA Recombinant Antibody (VMC193) | Neut, WB | Mouse IgG1 |
| NEUT-1232CQ | Mouse Anti-IL17RA Recombinant Antibody (clone CBL538) | WB, FC, CyTOF, Neut | Mouse IgG1 |
| NEUT-1233CQ | Mouse Anti-IL17RA Recombinant Antibody (clone MM0371-8D15) | WB, Neut | Mouse IgG1 |
| NEUT-1234CQ | Rabbit Anti-IL17RA Recombinant Antibody (clone CBL999) | Neut | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1794 | Rabbit Anti-IL17RA Recombinant Antibody (clone DS1794AB) | WB, IP, FC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-019LC | Rat Anti-Il17ra Recombinant Antibody (clone YC125) | FC, FuncS | Rat IgG |
| HPAB-0853-FY | Human Anti-IL17RA Recombinant Antibody (HPAB-0853-FY) | Activ | Human IgG |
| HPAB-0854-FY | Human Anti-IL17RA Recombinant Antibody (HPAB-0854-FY) | ELISA | Human IgG |
| HPAB-1557-FY | Human Anti-IL17RA Recombinant Antibody (HPAB-1557-FY) | FC, Inhib | Human IgG |
| VS-0723-WK267 | Rabbit Anti-IL17RA Recombinant Antibody (VS-0723-WK267) | ELISA, FC | Rabbit IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-134 | Afuco™ Anti-IL17RA Recombinant Antibody (AFC-TAB-134), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS, FC | Human IgG1, κ |
| AFC-TAB-217 | Afuco™ Anti-IL17RA ADCC Recombinant Antibody (Ixekizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0318-WJ-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0318-WJ-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0853-FY-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0853-FY-F(E)) | Activ | Human Fab |
| HPAB-0854-FY-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0854-FY-F(E)) | ELISA | Human Fab |
| HPAB-0144-WJ-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0144-WJ-S(P)) | ELISA | Humanized scFv |
| HPAB-1557-FY-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-1557-FY-F(E)) | FC | Human Fab |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0318-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0318-WJ-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0319-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0319-WJ-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0320-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0320-WJ-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0321-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0321-WJ-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0144-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0144-WJ-F(E)) | ELISA | Humanized Fab |
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