Recombinant Human Anti-IL17RA Soluble TCR (GA6) (KIH)
CAT#: VS-0622-YF7261
Human TCR (GA6) recognizes IL17RA peptide (FIMGISILL) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
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Specifications
- Host Species
- Human
- Target
- IL17RA
- Epitope
- FIMGISILL
- MHC
- HLA-A2
- Clone
- GA6
- Type
- Soluble TCR (KIH)
- Related Disease
- Rheumatoid arthritis
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- Interleukin 17 Receptor A variant FIT_TM; FIMGISILL
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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|---|---|---|---|
| HPAB-0318-WJ-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0318-WJ-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0319-WJ-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0319-WJ-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0320-WJ-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0320-WJ-S(P)) | ELISA, Neut | Humanized scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0318-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0318-WJ-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0319-WJ-F(E) | Human Anti-IL17RA Recombinant Antibody; Fab Fragment (HPAB-0319-WJ-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0853-FY-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0853-FY-S(P)) | Activ | Human scFv |
| HPAB-0854-FY-S(P) | Human Anti-IL17RA Recombinant Antibody; scFv Fragment (HPAB-0854-FY-S(P)) | ELISA | Human scFv |
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