Recombinant Human Anti-IL17RA Soluble TCR (GA6) (ZIP-Fos/ZIP-Jun)
CAT#: VS-0622-YF1845
Human TCR (GA6) recognizes IL17RA peptide (FIMGISILL) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (GA6). Please note that the activity is not guaranteed.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/if_selected.jpg
Normal Tissue
Figure 2 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_3.jpg
Normal Tissue
Figure 3 Liver
Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/24996/59803_A_7_4.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000177663-IL17RA
❮
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Specifications
- Host Species
- Human
- Target
- IL17RA
- Epitope
- FIMGISILL
- MHC
- HLA-A2
- Clone
- GA6
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Rheumatoid arthritis
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- Interleukin 17 Receptor A variant FIT_TM; FIMGISILL
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Datasheet
MSDS
COA
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