Mouse Anti-IL13RA2 (clone 2-7) scFv-Fc Chimera (CAT#: VS-0325-FY108)
The anti-IL13RA2 scFv-Fc antibody targets IL-13Rα2, a receptor involved in IL-13 signaling and immune responses. It is designed with a scFv-Fc fusion to enhance targeting efficiency and functional versatility. This antibody is valuable for studying IL-13Rα2-mediated pathways and its role in diseases like asthma and cancer.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/45831/1866_G1_31_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/45831/1866_G1_31_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/67363/1754_D2_3_cr57f3cf6655f7f_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/67363/1754_D2_3_cr57f3cf6655f7f_selected.jpg
Figure 3 RNA cell line category: Group enriched (PC-3, U-2197, U-251 MG, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123496-IL13RA2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000123496-IL13RA2
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human IL13RA2
- Species Reactivity
- Human
- Clone
- clone 2-7
- Applications
- ELISA, Flow Cytometry, Immunohistochemistry
- Related Disease
- Asthma and cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 13 Receptor Subunit Alpha 2
- Gene ID
- 3598
- UniProt ID
- Q14627
- Long Name
- Interleukin 13 Receptor Subunit Alpha 2
- Sequence Similarities
- Belongs to the type I cytokine receptor family. Type 5 subfamily.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Cleaved by MMP8 leading to a soluble form that is also able to interact with IL13.
Glycosylation at Asn115, Asn215, Asn290, and Asn299
Glycosylation from GlyGen 4 sites
- Protein Refseq
- XP_054183007.1; XP_054183008.1; NP_000631.1
- Function
- IL13RA2 (Interleukin 13 receptor subunit alpha 2) is a receptor for IL-13, involved in allergic inflammation and fibrosis. It acts as a decoy receptor or signaling receptor, influencing immune responses and tissue remodeling.
Recommended Products
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "IL13RA2"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Immunotoxin Products
Humanized Antibody Products
Mouse Antibody Products
IgM Antibody Products
Human Antibody Products
Chicken IgY Antibody Products
Blocking Antibody Products
Rabbit Monoclonal Antibody Products
MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-555 | Recombinant Anti-human IL13RA2 Antibody | WB, Neut, FuncS | IgG |
| MHH-555 | Recombinant Human Anti-human IL13RA2 Antibody | ELISA, IP, FuncS | IgG |
| MOB-0783CT | Recombinant Mouse anti-Human IL13RA2 Monoclonal antibody (EML442) | FC, ICC/IF, IHC-Fr, IHC-P, IP, WB | |
| HPAB-0999WJ | Mouse Anti-IL13RA2 Recombinant Antibody (clone FMMU-IL_13Ra 2-7) | ELISA, FC, IHC | Mouse IgG |
| HPAB-J0128-YC | Mouse Anti-IL13RA2 Recombinant Antibody (clone FMMU-IL-13R alpha 2-7) | ELISA, FC | Mouse IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0325-FY108. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
-2.png)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: WB, IF, FuncS
-1.jpg)
Application: IB, ELISA, FC, FuncS
-1.png)
Application: WB, ELISA
Application: ELISA, IHC, FC, IP, IF, Inhib
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
