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    Recombinant Anti-CCR5 Vesicular Antibody, EV Displayed (VS-0425-YC281)

    CAT#: VS-0425-YC281

    The Recombinant Anti-CCR5 Vesicular Antibody, EV Displayed (VS-0425-YC281) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CCR5-expressed cells or tissues. The CCR5 is a chemokine receptor associated with diseases like West Nile Virus, involved in immune system signaling pathways.

    Gene Expression
    ❮
    Figure 1 RNA cell line category: Cell line enhanced (JURKAT, Karpas-707, U-266/84)
    ❯

    Recombinant Antibody

    • Application
    • ELISA, FC, Neut, Cell-uptake
    • Product Type
    • Ab-Fc-EVs
    • Antibody Quantification (Ab/EV)
    • ~100 Ab/EV
    • Target
    • CCR5
    • Host Animal
    • Mouse
    • Antibody Isotype
    • IgG
    • Species Reactivity
    • Human
    • Expression Cell
    • Mammalian cell

    Engineered EVs

    • EV-sorting domain
    • CD63
    • Fc-binding domain
    • Protein A
    • EV Size
    • 30~150 nm
    • Producing Cell
    • HEK293F
    • Isolation Method
    • Gradient centrifugation
    • Purification
    • qEV size exclusion chromatography
    • Concentration
    • 1 x 10¹⁰
    • Size
    • 1 mL
    • Buffer
    • PBS
    • Storage
    • Store at -80°C for 12 months

    Target

    • Full Name
    • C-C motif chemokine receptor 5
    • Biological Process
    • Host-virus interaction
    • Molecular Function
    • G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer
    • Introduction
    • CCR5 (C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with CCR5 include West Nile Virus and Diabetes Mellitus, Insulin-Dependent, 22. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and phosphatidylinositol phospholipase C activity. An important paralog of this gene is CCR2.
    • Alternative Names
    • CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22
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    Datasheet

    Datasheet - VS-0425-YC281.pdf

    MSDS

    MSDS - VS-0425-YC281.pdf

    COA

    Certificate of Analysis Lookup

    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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