Recombinant Anti-CCR5 Vesicular Antibody, EV Displayed (VS-0425-YC281) (CAT#: VS-0425-YC281)

• Application
• ELISA, FC, Neut, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CCR5

• Host Animal
• Mouse

• Antibody Isotype
• IgG

• Species Reactivity
• Human

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• Protein A

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-C motif chemokine receptor 5

• Biological Process
• Host-virus interaction

• Molecular Function
• G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer

• Introduction
• CCR5 (C-C Motif Chemokine Receptor 5 (Gene/Pseudogene)) is a Protein Coding gene. Diseases associated with CCR5 include West Nile Virus and Diabetes Mellitus, Insulin-Dependent, 22. Among its related pathways are Cytokine Signaling in Immune system and Akt Signaling. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and phosphatidylinositol phospholipase C activity. An important paralog of this gene is CCR2.

• Alternative Names
• CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22

• Gene ID
• 1234

• UniProt ID
• P51681

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