Products
Loading...

CCR5

More+
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

Targets:
CCR5 & CD3
Type:
BiTE
Application:
FuncS, Promising therapeutic agent
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
BL, ELISA, FACS
Derivation:
Human
Type:
Fully human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Species Reactivity:
Did not react with CCR5 derived from rhesus macaques
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Derivation:
Human
Type:
Fully human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Type:
Human antibody
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Application:
For in vitro and in vivo research use. Not intended for any applications in human.
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
BL, ELISA, FACS
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
45-1 Ramsey Road, Shirley, NY 11967, USA     Tel: 1-631-381-2994    Fax: 1-631-207-8356    Email:
Terms of Service-Privacy Policy     © 2007 - 2018 Creative-Biolabs All Rights Reserved