Recombinant Anti-CSF2RA Vesicular Antibody, EV Displayed (VS-0425-YC411)

CAT#: VS-0425-YC411

The Recombinant Anti-CSF2RA Vesicular Antibody, EV Displayed (VS-0425-YC411) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CSF2RA-expressed cells or tissues. The CSF2RA is a receptor subunit involved in cytokine signaling, associated with conditions like pulmonary alveolar proteinosis.

Gene Expression
Figure 1 IHC staining of human skin Figure 2 Cerebral cortex Figure 3 Colon Figure 4 Kidney Figure 5 Testis Figure 6 Placenta Figure 7 Lymph node Figure 8 RNA cell line category: Group enriched (BEWO, HMC-1, SK-MEL-30)

Recombinant Antibody

  • Application
  • ELISA, FC, Neut, Cell-uptake
  • Product Type
  • Ab-Fc-EVs
  • Antibody Quantification (Ab/EV)
  • ~100 Ab/EV
  • Target
  • CSF2RA
  • Host Animal
  • Human
  • Antibody Isotype
  • IgG
  • Species Reactivity
  • Human
  • Expression Cell
  • Mammalian cell

Engineered EVs

  • EV-sorting domain
  • CD63
  • Fc-binding domain
  • z domain
  • EV Size
  • 30~150 nm
  • Producing Cell
  • HEK293F
  • Isolation Method
  • Gradient centrifugation
  • Purification
  • qEV size exclusion chromatography
  • Binding Affinity
  • Kd = 0.85 µg/mL
  • Concentration
  • 1 x 10¹⁰
  • Size
  • 1 mL
  • Buffer
  • PBS
  • Storage
  • Store at -80°C for 12 months

Target

  • Full Name
  • Colony stimulating factor 2 receptor subunit alpha
  • Molecular Function
  • Receptor
  • Introduction
  • CSF2RA (Colony Stimulating Factor 2 Receptor Alpha Subunit) is a Protein Coding gene. Diseases associated with CSF2RA include Surfactant Metabolism Dysfunction, Pulmonary, 4 and Hereditary Pulmonary Alveolar Proteinosis. Among its related pathways are RET signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor activity and cytokine receptor activity. An important paralog of this gene is IL3RA.
  • Alternative Names
  • alphaGMR, CD116, CSF2R
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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