Recombinant Anti-CSF2RA Vesicular Antibody, EV Displayed (VS-0425-YC411) (CAT#: VS-0425-YC411)
The Recombinant Anti-CSF2RA Vesicular Antibody, EV Displayed (VS-0425-YC411) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CSF2RA-expressed cells or tissues. The CSF2RA is a receptor subunit involved in cytokine signaling, associated with conditions like pulmonary alveolar proteinosis.
Specific Inquiry
Normal Tissue
RNA Expression

Figure 1 IHC staining of human skin
(Immunohistochemical staining of human skin shows distinct cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/ihc_selected.jpg
(Immunohistochemical staining of human skin shows distinct cytoplasmic positivity in epidermal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/ihc_selected.jpg

Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_B_9_5.jpg

Figure 3 Colon
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_7_3.jpg
(Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_7_3.jpg

Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_8_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_8_5.jpg

Figure 5 Testis
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_6_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_6_6.jpg

Figure 6 Placenta
(Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_3_7.jpg
(Decidual cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_3_7.jpg

Figure 7 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_9_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16148/35783_A_9_8.jpg

Figure 8 RNA cell line category: Group enriched (BEWO, HMC-1, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198223-CSF2RA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198223-CSF2RA
Recombinant Antibody
- Application
- ELISA, FC, Neut, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CSF2RA
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Colony stimulating factor 2 receptor subunit alpha
- Molecular Function
- Receptor
- Introduction
- CSF2RA (Colony Stimulating Factor 2 Receptor Alpha Subunit) is a Protein Coding gene. Diseases associated with CSF2RA include Surfactant Metabolism Dysfunction, Pulmonary, 4 and Hereditary Pulmonary Alveolar Proteinosis. Among its related pathways are RET signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include receptor activity and cytokine receptor activity. An important paralog of this gene is IL3RA.
- Alternative Names
- alphaGMR, CD116, CSF2R
- Gene ID
- 1438
- UniProt ID
- P15509
Downloads
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2501z | Mouse Anti-CSF2RA Recombinant Antibody (clone 23G1) | WB, FC, IHC, IP | Mouse IgG1 |
PABL-106 | Human Anti-CSF2RA Recombinant Antibody (PABL-106) | WB, Neut, FuncS | Human IgG |
PABL-107 | Human Anti-CSF2RA Recombinant Antibody (PABL-107) | WB, Neut, FuncS | Human IgG |
MOB-1738MZ | Recombinant Mouse Anti-Human CSF2RA Antibody (clone 5I2) | FC | Mouse antibody |
MRO-1900-CN | Rabbit Anti-CSF2RA Polyclonal Antibody (MRO-1900-CN) | WB, IF, IHC, FC | Rabbit IgG |
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