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CSF2RA
Loading...Anti-CSF2RA Products
- Human Anti-CSF2RA Antibody, mRNA (AGTO-L008D-mRNA)
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- Species Reactivity: Human
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- Rabbit Anti-CSF2RA Polyclonal Antibody (MRO-1900-CN) (MRO-1900-CN)
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- Species Reactivity: Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Rat Anti-Csf2ra Recombinant Antibody (clone CBL639) (NEUT-533CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: FC, CyTOF®, ICC, Neut
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- GM-CSF-DT immunotoxin (AGTO-L008D)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Human Anti-CSF2RA scFv-Fc Chimera (VS-0425-FY113) (VS-0425-FY113)
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- Species Reactivity: Human
- Type: Human IgG4, scFv-Fc
- Application: ELISA, FC
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- Species Reactivity: Human
- Target: CSF2RA
- Host Animal: Human
- Application: ELISA, FC, Neut, Cell-uptake
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- Anti-CSF2RA Immunohistochemistry Kit (VS-0525-XY1708)
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- Species Reactivity: Human
- Target: CSF2RA
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
Protein class
Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (monocytes, Langerhans cells, Syncytiotrophoblasts, Cytotrophoblasts, Extravillous trophoblasts, Macrophages)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Group enriched (BEWO, HMC-1, SK-MEL-30)
Interaction
Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits.
Molecular function
Receptor
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