Recombinant Anti-CSPG4 Vesicular Antibody, EV Displayed (VS-0425-YC269)
CAT#: VS-0425-YC269
The Recombinant Anti-CSPG4 Vesicular Antibody, EV Displayed (VS-0425-YC269) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CSPG4-expressed cells or tissues. The CSPG4 is a pseudogene for a chondroitin sulfate proteoglycan.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SK-MEL-30
Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1933/1898_E12_17_cr5f68f3ec906de_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/50008/782_C2_1_selected.jpg
Normal Tissue
Figure 3 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity, with a granular pattern, in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2951/ihc_selected.jpg
Normal Tissue
Figure 4 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/16189/ihc_selected.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2951/10455_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2951/10455_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (BJ, SK-MEL-30, U-138 MG, WM-115)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000173546-CSPG4
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CSPG4
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Chondroitin sulfate proteoglycan 4
- Biological Process
- Angiogenesis, Differentiation, Tissue remodeling
- Molecular Function
- Developmental protein, Transducer
- Cellular Localization
- Plasma membrane
- Introduction
- CSPG4P1Y (Chondroitin Sulfate Proteoglycan 4 Pseudogene 1, Y-Linked) is a Pseudogene.
- Alternative Names
- CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2
- Gene ID
- 1464
- UniProt ID
- Q6UVK1
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G013E | Anti-CSPG4 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
| AGTO-G013S | Anti-CSPG4 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study | |
| AGTO-G014E | Anti-CSPG4 immunotoxin (IgG)-PE | Cytotoxicity assay, Function study | |
| AGTO-G014S | Anti-CSPG4 immunotoxin (IgG)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-102CT | Anti-Human CSPG4 Recombinant Antibody (D2A-1H10) | ELISA, WB | Human antibody |
| TAB-102CT-S(P) | Anti-Human CSPG4 Recombinant Antibody scFv Fragment (D2A-1H10) | ELISA, WB | Human antibody |
| TAB-102CT-F(E) | Anti-Human CSPG4 Recombinant Antibody Fab Fragment (D2A-1H10) | ELISA, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-103CT | Mouse Anti-CSPG4 Recombinant Antibody (TAB-103CT) | Funcs, FC, ELISA, WB | Mouse IgG |
| TAB-104CT | Mouse Anti-CSPG4 Recombinant Antibody (TAB-104CT) | IB, IF, IHC, FC | Mouse IgG |
| TAB-105CT | Human Anti-CSPG4 Recombinant Antibody (TAB-105CT) | FC, ELISA, WB, Inhib | Human IgG |
| TAB-103CT-F(E) | Mouse Anti-CSPG4 Recombinant Antibody; Fab Fragment (TAB-103CT-F(E)) | FC, ELISA, WB | Mouse Fab |
| TAB-104CT-F(E) | Mouse Anti-CSPG4 Recombinant Antibody; Fab Fragment (TAB-104CT-F(E)) | FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-550CQ | Mouse Anti-CSPG4 Recombinant Antibody (clone 9.2.27) | EM, Block, IP, FC, ICC, IF | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0840 | Hi-Affi™ Rabbit Anti-CSPG4 Recombinant Antibody (clone DS840AB) | WB, IHC, FC | Rabbit IgG |
| MOR-0105-FY | Rabbit Anti-CSPG4 Recombinant Antibody (clone AFY0076) | ICC, IF, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0071-LSX | Mouse Anti-CSPG4 Recombinant Antibody (HPAB-0071-LSX) | ELISA | Mouse IgG1 |
| HPAB-0072-LSX | Mouse Anti-CSPG4 Recombinant Antibody (HPAB-0072-LSX) | ELISA | Mouse IgG1 |
| HPAB-0073-LSX | Human Anti-CSPG4 Recombinant Antibody (clone D2A-1H10-UC8) | ELISA, WB | Human IgG |
| HPAB-0074-LSX | Human Anti-CSPG4 Recombinant Antibody (clone D2A-1H10-UC12) | ELISA, WB | Human IgG |
| HPAB-0075-LSX | Human Anti-CSPG4 Recombinant Antibody (HPAB-0075-LSX) | ELISA | Chimeric (mouse/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0070-LSX-S(P) | Mouse Anti-CSPG4 Recombinant Antibody; scFv Fragment (HPAB-0070-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0071-LSX-S(P) | Mouse Anti-CSPG4 Recombinant Antibody; scFv Fragment (HPAB-0071-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0072-LSX-S(P) | Mouse Anti-CSPG4 Recombinant Antibody; scFv Fragment (HPAB-0072-LSX-S(P)) | ELISA | Mouse scFv |
| HPAB-0073-LSX-S(P) | Human Anti-CSPG4 Recombinant Antibody (clone D2A-1H10-UC8); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-0074-LSX-S(P) | Human Anti-CSPG4 Recombinant Antibody (clone D2A-1H10-UC12); scFv Fragment | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0070-LSX-F(E) | Mouse Anti-CSPG4 Recombinant Antibody; Fab Fragment (HPAB-0070-LSX-F(E)) | ELISA | Mouse Fab |
| HPAB-0071-LSX-F(E) | Mouse Anti-CSPG4 Recombinant Antibody; Fab Fragment (HPAB-0071-LSX-F(E)) | ELISA | Mouse Fab |
| HPAB-0079-FY-F(E) | Human Anti-CSPG4 Recombinant Antibody (clone M4-3 ML2); Fab Fragment | ELISA | Humanized Fab |
| HPAB-595-FY-F(E) | Human Anti-CSPG4 Recombinant Antibody; Fab Fragment (HPAB-595-FY-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-644-FY-F(E) | Mouse Anti-CSPG4 Recombinant Antibody Fab Fragment (HPAB-644-FY-F(E)) | FC, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY61 | Human Anti-CSPG4 (clone D2A-1H10) scFv-Fc Chimera | ELISA, WB, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1731 | Anti-Mouse CSPG4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY1732 | Anti-Rat CSPG4 Immunohistochemistry Kit | IHC |
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