Recombinant Anti-EFNB2 Vesicular Antibody, EV Displayed (VS-0425-YC163) (CAT#: VS-0425-YC163)

• Application
• Block, ELISA, FC, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• EFNB2

• Host Animal
• Human

• Antibody Isotype
• IgG

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• Ephrin B2

• Biological Process
• Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis

• Molecular Function
• Developmental protein, Host cell receptor for virus entry, Receptor

• Cellular Localization
• Nucleoplasm, Cytosol

• Introduction
• This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

• Alternative Names
• EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228

• Gene ID
• 1948

• UniProt ID
• P52799

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