Recombinant Anti-EFNB2 Vesicular Antibody, EV Displayed (VS-0425-YC163)
CAT#: VS-0425-YC163
The Recombinant Anti-EFNB2 Vesicular Antibody, EV Displayed (VS-0425-YC163) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to EFNB2-expressed cells or tissues. The EFNB2 is an ephrin class B protein involved in developmental events, binding to EPHB4 and EPHA3 receptors.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/47_A4_1_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/9368/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human kidney
Immunohistochemical staining of human kidney shows moderate cytoplasmic positivity in cells in tubules and cells in glomeruli.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_8_5_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_9_3.jpg
Normal Tissue
Figure 6 Liver
Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_8_4.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_7_5.jpg
Normal Tissue
Figure 8 Testis
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_A_5_6.jpg
Normal Tissue
Figure 9 Skin
Endothelial cells
Staining: Medium
Intensity: Moderate
Fibrohistiocytic cells
Staining: Medium
Intensity: Moderate
Lymphocytes
Staining: Medium
Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/8999/26099_B_7_1.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (AF22, OE19, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125266-EFNB2
❮
❯
Recombinant Antibody
- Application
- Block, ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- EFNB2
- Host Animal
- Human
- Antibody Isotype
- IgG
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Ephrin B2
- Biological Process
- Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis
- Molecular Function
- Developmental protein, Host cell receptor for virus entry, Receptor
- Cellular Localization
- Nucleoplasm, Cytosol
- Introduction
- This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
- Alternative Names
- EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228
- Gene ID
- 1948
- UniProt ID
- P52799
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Datasheet
MSDS
COA
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See other products for "EFNB2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-304-F(E) | Recombinant Anti-human EFNB2 Antibody Fab Fragment | IP, FuncS | Fab |
| HPAB-0164-LSX-F(E) | Human Anti-EFNB2 Recombinant Antibody (clone A11); Fab Fragment | ELISA | Human Fab |
| HPAB-0165-LSX-F(E) | Human Anti-EFNB2 Recombinant Antibody (clone B1); Fab Fragment | ELISA | Human Fab |
| HPAB-0166-LSX-F(E) | Human Anti-EFNB2 Recombinant Antibody (clone D1); Fab Fragment | ELISA | Human Fab |
| HPAB-0167-LSX-F(E) | Human Anti-EFNB2 Recombinant Antibody (clone E2); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-304 | Recombinant Human Anti-human EFNB2 Antibody | WB, IHC, FuncS | IgG |
| HPAB-0164-LSX | Human Anti-EFNB2 Recombinant Antibody (clone A11) | ELISA | Human IgG |
| HPAB-0165-LSX | Human Anti-EFNB2 Recombinant Antibody (clone B1) | ELISA | Human IgG |
| HPAB-0166-LSX | Human Anti-EFNB2 Recombinant Antibody (clone D1) | ELISA | Human IgG |
| HPAB-0167-LSX | Human Anti-EFNB2 Recombinant Antibody (clone E2) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-304-S(P) | Recombinant Human Anti-human EFNB2 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
| HPAB-0164-LSX-S(P) | Human Anti-EFNB2 Recombinant Antibody (clone A11); scFv Fragment | ELISA | Human scFv |
| HPAB-0165-LSX-S(P) | Human Anti-EFNB2 Recombinant Antibody (clone B1); scFv Fragment | ELISA | Human scFv |
| HPAB-0166-LSX-S(P) | Human Anti-EFNB2 Recombinant Antibody (clone D1); scFv Fragment | ELISA | Human scFv |
| HPAB-0167-LSX-S(P) | Human Anti-EFNB2 Recombinant Antibody (clone E2); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-389MZ | Anti-Human EFNB2 Recombinant Antibody (2B1) | Block, FuncS, Inhib, WB | Human antibody |
| TAB-390MZ | Anti-Human EFNB2 Recombinant Antibody (B11) | Block, FuncS, Inhib, WB | Human antibody |
| TAB-391MZ | Anti-Human EFNB2 Recombinant Antibody (A1) | ELISA | Human antibody |
| TAB-392MZ | Anti-Human EFNB2 Recombinant Antibody (E4 ) | ELISA | Human antibody |
| TAB-393MZ | Anti-Human EFNB2 Recombinant Antibody (TAB-393MZ) | IHC, ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1100 | Hi-Affi™ Rabbit Anti-EFNB2 Recombinant Antibody (clone DS1100AB) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2176 | Anti-EFNB2 Immunohistochemistry Kit | IHC |
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